Recently it has been demonstrated that catanionic mixtures of oppositely charged surfactants have improved physicochemical-biological properties compared to the individual components. Isotherms of mixtures of an anionic biosurfactant (lichenysin) and a cationic aminoacid surfactant (C(LA)) indicate a strong interaction suggesting the formation of a new "pseudo-surfactant". The antimicrobial properties of the mixture lichenysin and C(LA) M80:20, indicate a synergistic effect of the components. The mechanism of action on the bacterial envelope was assessed by flow cytometry and Transmission Electron Microscopy.
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| http://dx.doi.org/10.1016/j.colsurfb.2016.10.008 | DOI Listing |
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Lichenysin-geminal amino acid-based surfactants: Synergistic action of an unconventional antimicrobial mixture.
Colloids Surf B Biointerfaces
January 2017
Laboratori de Microbiologia, Facultat de Farmacia, Universitat de Barcelona, Joan XXIII s/n, 08028 Barcelona, Spain. Electronic address:
Recently it has been demonstrated that catanionic mixtures of oppositely charged surfactants have improved physicochemical-biological properties compared to the individual components. Isotherms of mixtures of an anionic biosurfactant (lichenysin) and a cationic aminoacid surfactant (C(LA)) indicate a strong interaction suggesting the formation of a new "pseudo-surfactant". The antimicrobial properties of the mixture lichenysin and C(LA) M80:20, indicate a synergistic effect of the components.
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