Reproducibility and transparency in biomedical sciences.

Oral Dis

Center for Clinical Research, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.

Published: October 2017

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385161PMC
http://dx.doi.org/10.1111/odi.12588DOI Listing

Publication Analysis

Top Keywords

reproducibility transparency
4
transparency biomedical
4
biomedical sciences
4
reproducibility
1
biomedical
1
sciences
1

Similar Publications

[Interpretation of the transparent reporting of a multivariable prediction model for individual prognosis or diagnosis based on regression or machine learning methods (TRIPOD+AI)].

Zhonghua Nei Ke Za Zhi

January 2025

Chinese Academy of Medical Sciences, Peking Union Medical College, National Center for Cardiovascular Diseases, National Clinical Medical Research Center for Cardiovascular Diseases, Fu Wai Hospital Medical Research and Statistics Center, Beijing100037, China.

View Article and Find Full Text PDF

Biomarkers.

Alzheimers Dement

December 2024

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.

Background: To understand the progression of Alzheimer's disease (AD), neuroimaging and biomarker research relies increasingly on sophisticated data analysis techniques that are often restricted to expert lab environments. Here, we demonstrate how complex analyses on modeling tau spreading across interconnected brain regions from our previous studies (e.g.

View Article and Find Full Text PDF

Breast cancer continues to be a major health concern, and early detection is vital for enhancing survival rates. Magnetic resonance imaging (MRI) is a key tool due to its substantial sensitivity for invasive breast cancers. Computer-aided detection (CADe) systems enhance the effectiveness of MRI by identifying potential lesions, aiding radiologists in focusing on areas of interest, extracting quantitative features, and integrating with computer-aided diagnosis (CADx) pipelines.

View Article and Find Full Text PDF

Background: The narrative review aims to explore CRC pathogenesis by deciphering genetic-environmental interactions, analyzing the tumor microenvironment's role, and assessing treatment responses. These objectives seek to enhance clinical decision-making and improve CRC patient care through a comprehensive understanding of the disease.

Methods: A narrative review from 2019 to 2024 on colorectal cancer (CRC) pathogenesis and treatment strategies was conducted.

View Article and Find Full Text PDF

The TRIPOD-LLM reporting guideline for studies using large language models.

Nat Med

January 2025

Artificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Harvard Medical School, Boston, MA, USA.

Large language models (LLMs) are rapidly being adopted in healthcare, necessitating standardized reporting guidelines. We present transparent reporting of a multivariable model for individual prognosis or diagnosis (TRIPOD)-LLM, an extension of the TRIPOD + artificial intelligence statement, addressing the unique challenges of LLMs in biomedical applications. TRIPOD-LLM provides a comprehensive checklist of 19 main items and 50 subitems, covering key aspects from title to discussion.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!