A practical oxidative C-H functionalization of N-carbamoyl tetrahydro-β-carbolines with diverse potassium trifluoroborates.

A practical and mild metal-free oxidative C-H functionalization of N-carbamoyl tetrahydro-β-carbolines has been reported. This reaction has excellent functional group tolerance, and exhibits a broad range of potassium trifluoroborate components, allowing for the facile C-H functionalization of electronically varied N-carbamoyl THCs in high efficiency with excellent regioselectivity.