Magnetite nanoparticles combined with polymers produce white-light emission under multiphoton laser irradiation. Understanding the photonic reaction in magnetite-polymer composites is critical for application of magnetite NPs as photothermal agents. Laser irradiated magnetite nanoparticle-poly(methyl methacrylate) (PMMA) composites exhibit fluorescence due to the carbon double-bond formation resulting from the oxidation of the PMMA.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c6nr04408e | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Therapeutic Black Phosphorus Nanosheets Elicit Neutrophil Response for Enhanced Tumor Suppression.
Adv Sci (Weinh)
January 2025
Department of General Surgery, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230036, P. R. China.
Black phosphorus (BP) has demonstrated potential as a drug carrier and photothermal agent in cancer therapy; however, its intrinsic functions in cancer treatment remain underexplored. This study investigates the immunomodulatory effects of polyethylene glycol-functionalized BP (BP-PEG) nanosheets in breast cancer models. Using immunocompetent mouse models-including 4T1 orthotopic BALB/c mice and MMTV-PyMT transgenic mice, it is found that BP-PEG significantly inhibits tumor growth and metastasis without directly inducing cytotoxicity in tumor cells.
View Article and Find Full Text PDFMultifunctional biosynthesized magnetosome for multimodal imaging and combined therapy of tumor.
Mater Today Bio
February 2025
Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China.
The large recruitment of tumor-associated macrophages and low exposure of tumor-associated antigens in tumor microenvironment have severely suppress the efficacy of anti-tumor immunotherapy. Herein, biosynthesized magnetosome (Mag) from bacteria was loaded with photothermal/photodynamic agent/near infrared (NIR) fluorescence dye (IR780) and further modified with lipid-PEG-c(RGDyK) through biomembrane, forming Mag for fluorescence imaging, magnetic resonance imaging, immunotherapy and photodynamic/photothermal therapy. After intravenous injection into B16F10 tumor-bearing mice, Mag could efficiently accumulate in tumor tissues based on near infrared (NIR) fluorescence and magnetic resonance dual-modality imaging, and repolarize tumor-associated macrophages (TAMs) from M2 phenotype to M1 phenotype, significantly improving the effect of tumor immunotherapy.
View Article and Find Full Text PDFApplication of Multifunctional Metal Nanoparticles in the Treatment of Glioma.
Int J Nanomedicine
January 2025
Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221002, People's Republic of China.
Glioma is the most common primary malignant brain tumor with a poor survival rate. It is characterized by diffuse and invasive growth and heterogeneity, which limits tumor identification and complete resection. Therefore, the precise detection and postoperative adjuvant therapy of gliomas have become increasingly important and urgent.
View Article and Find Full Text PDFA Spiro-Based NIR-II Photosensitizer with Efficient ROS Generation and Thermal Conversion Performances for Imaging-Guided Tumor Theranostics.
Adv Healthc Mater
January 2025
Center for Molecular Systems and Organic Devices (CMSOD), Key Laboratory for Organic Electronics & Information Displays (KLOEID) and Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications (NJUPT), Nanjing, 210023, China.
Organic photosensitizers (PSs) possessing NIR-II emission and photodynamic/photothermal effect have received a great sense of attention for their cutting-edge applications in imaging-guided multimodal phototherapy. However, it is highly challenging to design efficient PSs with high luminescence and phototherapy performance simultaneously. In this study, a spiro-functionalization strategy is proposed to alleviate aggregate-caused quenching of PSs and promote photodynamic therapy, and the strategy is verified via a spiro[fluorine-9,9'-xanthene]-modified NIR-II PS (named SFX-IC) with an acceptor-donor-acceptor configuration.
View Article and Find Full Text PDFRational Design of Quinoidal Conjugated Polymers for Photothermal Antibacterial Therapy.
Macromol Rapid Commun
January 2025
School of Materials Science and Engineering, Hebei University of Technology, Tianjin, 300401, P. R. China.
The increasing prevalence of antibiotic resistance, driven by the overuse and misuse of conventional antibiotics, has become a critical public health concern. Photothermal antibacterial therapy (PTAT) utilizes heat generated by photothermal agents under light exposure to inhibit bacterial growth without inducing resistance, attracting more and more attention. Quinoid conjugated polymers, especially para-azaquinodimethane (AQM) polymer, are a class of organic semiconductors known for efficient π-electron delocalization, near-infrared absorption, and narrow bandgap, showing great potential in the application of photothermal reagents.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!