To complete the review article by Abes and colleagues (Pharmaceuticals 2010, 3, 146-157) which provides a good overview on recently developed approaches for generation of glyco-modified antibodies and the impact of glyco-modification of antibodies on their effector functions, important information should be added, namely that - besides the Glycart and the Biowa approach to generate de-fucosylated antibodies - innovative, moss derived methods have been shown to generate glyco-modified antibodies with improved effector function profile.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033957 | PMC |
| http://dx.doi.org/10.3390/ph3061887 | DOI Listing |
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