AI Article Synopsis
- Syndromic craniosynostosis occurs in about 1 in 30,000 live births, resulting in unique craniofacial deformities and potential cognitive impairments, with over 150 associated syndromes.
- The article outlines common features of syndromic synostosis, differentiates between syndromic and secondary synostosis, and emphasizes the need for comprehensive medical histories and examinations.
- It also covers the significance of adjuvant testing and a multidisciplinary approach to management for affected individuals.
Article Abstract
Syndromic craniosynostosis affects up to 1:30,000 live births with characteristic craniofacial growth restrictions, deformities, and other associated abnormalities, such as carpal-pedal anomalies and cognitive function impairment. More than 150 syndromes are associated with craniosynostosis. This article describes some commonalities and distinguishing features and management of syndromic synostosis. Also addressed is secondary synostosis, which is often found in syndromic children with problems related to microcephaly, hydrocephalus, or shunt-induced craniosynostosis, although pathophysiologically and genetically different. The importance of obtaining a thorough history and a complete physical and examination is highlighted. Adjuvant testing and multidisciplinary management are discussed.
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| http://dx.doi.org/10.1016/j.fsc.2016.06.008 | DOI Listing |
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