Objective: To investigate the relationship between haematological routine parameters and audiogram shapes in patients affected by sudden sensorineural hearing loss (SSNHL).
Design: A retrospective study. All patients were divided into four groups according to the audiometric curve and mean values of haematological parameters (haemoglobin, white blood cell, neutrophils and lymphocytes relative count, platelet count, haematocrit, prothrombin time, activated partial thromboplastin time, fibrinogen and neutrophil-to-lymphocite ratio) of each group were statistically compared. The prognostic role of blood profile and coagulation test was also examined.
Study Sample: A cohort of 183 SSNHL patients without comorbidities.
Results: With a 48.78% of complete hearing recovery, individuals affected by upsloping hearing loss presented a better prognosis instead of flat (18.36%), downsloping (19.23%) and anacusis (2.45%) groups (p = 0.0001). The multivariate analysis of complete blood count values revealed lower mean percentage of lymphocytes (p = 0.041) and higher platelet levels (p = 0.015) in case of downsloping hearing loss; with the exception of fibrinogen (p = 0.041), none of the main haematological parameters studied resulted associated with poorer prognosis.
Conclusions: Our work suggested a lack of association between haematological parameters and a defined audiometric picture in SSNHL patients; furthermore, only fibrinogen seems to influence the prognosis of this disease.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14992027.2016.1236418 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Exploring the Intricate Connection Between Vitamin B12 Deficiency and Hearing Loss: A Systematic Literature Review.
Ear Nose Throat J
January 2025
Department of Audiology and Speech Language Pathology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Karnataka, Manipal, India.
Vitamin B12 is an essential nutrient crucial for overall health, and deficiencies can lead to hearing loss. The aim of the systematic review was to explore the intricate connection between vitamin B12 deficiency and hearing loss using a systematic literature review. A systematic literature search was carried out to identify the articles exploring the connection between vitamin B12 deficiency and hearing loss.
View Article and Find Full Text PDFPrevalence of High Frequency Noise-Induced Hearing Loss Among Medical Students Using Personalized Listening Devices.
J Clin Med
December 2024
Department of Otorhinolaryngology, Head and Neck Surgery, Bhaarath Medical College, Chennai 600073, Tamil Nadu, India.
The misuse of personalized listening devices (PLDs) resulting in noise-induced hearing loss (NIHL) has become a public health concern, especially among youths, including medical students. The occupational use of PLDs that produce high-intensity sounds amplifies the danger of cochlear deterioration and high-frequency NIHL especially when used in noisy environments. This study aims to evaluate the incidence and trends of NIHL among medical students using PLDs.
View Article and Find Full Text PDFExploring the Hearing Improvement and Parental Stress in Children with Hearing Loss Using Hearing Aids or Cochlear Implants.
J Clin Med
December 2024
Unit of Otorhinolaryngology, Department of Adult and Development Age Human Pathology "Gaetano Barresi", University of Messina, 98122 Messina, Italy.
This study aims to describe the stress levels experienced by parents of children with hearing loss who use conventional hearing aids or cochlear implants, and to assess the correlation between parental stress and the auditory skills acquired by the children. The study was conducted at the Policlinic "Gaetano Martino" in Messina, evaluating data from 42 pairs of parents of children using hearing aids or cochlear implants. Parents completed the LittlEARS Auditory Questionnaire (LEAQ) and the Parental Stress Scale (PSS) 18 months after the initial device (hearing aid or cochlear implant) had been activated.
View Article and Find Full Text PDFCochlear Mechanics Are Preserved After Inner Ear Delivery of Gold Nanoparticles.
Int J Mol Sci
December 2024
Caruso Department of Otolaryngology-Head and Neck Surgery, University of Southern California, Los Angeles, CA 90033, USA.
Novel therapeutic delivery systems and delivery methods to the inner ear are necessary to treat hearing loss and inner ear disorders. However, numerous barriers exist to therapeutic delivery into the bone-encased and immune-privileged environment of the inner ear and cochlea, which makes treating inner ear disorders challenging. Nanoparticles (NPs) are a type of therapeutic delivery system that can be engineered for multiple purposes, and posterior semicircular canal (PSCC) infusion is a method to directly deposit them into the cochlea.
View Article and Find Full Text PDFAuditory Brainstem Response (ABR) Recording of Simultaneous Electric-Acoustic Stimulation between Round Window Membrane and Basal Part of Cochlear Bone in guinea Pigs.
Otol Neurotol
January 2025
Department of Otolaryngology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Hypothesis: Extracochlear electric-acoustic stimulation (EAS) between the round window membrane and the basal part of the cochlear bone exhibits distinct auditory brainstem response (ABR) characteristics.
Background: The use of EAS in individuals with residual hearing is becoming increasingly common in clinical settings. Ongoing research has explored the characteristics of EAS-induced responses in hearing cochleae.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!