A facile strategy for accessing 3-alkynylchromones through gold-catalyzed alkynylation/cyclization of o-hydroxyarylenaminones.

Chem Commun (Camb)

Division of Organic Chemistry, CSIR-National Chemical Laboratory, Dr Homi Bhabha Road, Pune-411 008, India. and Academy of Scientific and Innovative Research (AcSIR), New Delhi-110 025, India.

Published: October 2016

A strategy based on tandem alkynylation of o-hydroxyarylenaminones followed by intramolecular cyclization has been developed to generate a diverse array of 3-alkynyl chromones. The functionality embedded in these key intermediates enables their facile elaboration into more diverse structures by a variety of functionalizations and ring-forming processes.

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Source
http://dx.doi.org/10.1039/c6cc07119hDOI Listing

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