An observed case of ovarian pregnancy after intraperitoneal insemination (IPI) triggers a description of this new technique and a suggestion as to the possible dynamics of the ensuing ectopic pregnancy.
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Intraperitoneal rupture of a degenerated uterine fibroid during pregnancy: A case report and literature review.
Radiol Case Rep
March 2025
Tunis Maternity and Neonatology Center, Department 'C' of Gynecology and Obstetrics, Tunis, Tunisia.
This case report describes a rare instance of intraperitoneal rupture in a redegenerated uterine fibroid during pregnancy. A 38-year-old woman at 38 weeks gestation, with a history of a single pregnancy, presented with mild pelvic pain persisting through late pregnancy. An emergency caesarean section was performed due to acute fetal distress during labor.
View Article and Find Full Text PDFInvestigating intrauterine exposure to methamphetamine on serine-threonine kinase pathway in male rat testis.
Cell Mol Biol (Noisy-le-grand)
January 2025
Department of Physiology, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Article Synopsis
- Intrauterine exposure to methamphetamine (METH) during pregnancy negatively impacts testicular development in offspring, leading to apoptosis in spermatids.
- Research focused on proteins involved in sperm growth pathways, particularly TSSK and RIPK2, showing significant changes in their expression levels due to METH exposure.
- Findings indicated that METH exposure resulted in decreased TSSK expression, increased RIPK2 expression, thinner germ layers, more inflammatory cells, and a reduction in the thickness of seminiferous tubules in rat testes.
Efficacy of umbilical cord-derived mesenchymal stem cells and exosomes in conjunction with standard IBD drug on immune responses in an IBD mouse model.
Stem Cell Res Ther
January 2025
Department of Medical Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Background: Inflammatory bowel disease (IBD) is a persistent inflammation of the digestive system, and Mesenchymal Stem Cells (MSCs) and their exosomes have demonstrated potential as treatments for this condition. The objective of this research was to examine the possible effectiveness of intraperitoneal injection of umbilical cord-MSCs (UC-MSCs) and their exosomes through a two-time injection regimen in a mouse model.
Method: In this study, an animal model of a specific type of IBD in C57BL/6 mice, induced by dextran sulfate sodium (DSS), was utilized.
Maternal immunization impairs lymphoma growth and CNS/ocular metastasis in the offspring.
Front Immunol
January 2025
Alexander Silberman Institute of Life Science, The Hebrew University of Jerusalem, Jerusalem, Israel.
Maternal immunization is an important tool directed against a variety of infectious maladies in the offspring. A complementary, but less explored area is the use of maternal immunization in the prevention and treatment of childhood cancers. This in part stems from the lack of adequate experimental model systems.
View Article and Find Full Text PDFCritical procedural steps in intrauterine transfusion: Delphi survey of international experts.
Ultrasound Obstet Gynecol
January 2025
Division of Fetal Medicine, Department of Obstetrics and Gynecology, Willem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, The Netherlands.
Objective: To determine consensus, using Delphi methodology, on the critical procedural steps for intravascular intrauterine transfusion (IUT) for the treatment of fetal anemia.
Methods: We conducted a two-part Delphi survey of international experts in fetal intervention. The first round of the survey proposed 32 potentially critical steps for the IUT procedure.
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