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Nutrition Module: Addressing the Nutrition Education Gap in Undergraduate Medical Curricula via a Novel Approach.
Med Sci Educ
December 2024
Department of Neurology, Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, NC USA.
Article Synopsis
- Many medical curricula lack sufficient nutrition education, which is crucial for health outcomes.
- A new online nutrition module was developed and tested on 15 medical students, showing a significant increase in knowledge from pre-assessment to post-assessment.
- The module was effective in teaching essential nutrition topics and demonstrated that students retained most of the information even two months later.
Impact of nuclear fragmentation on the stopping power ratio ofC ion beams.
Phys Med Biol
December 2024
Department of Medical Radiation Physics, Carl von Ossietzky University Oldenburg, Oldenburg, Germany.
: Nuclear fragmentation generates a diverse dosimetric environment in the path ofC ion beams. Concise parametrization of the beam's composition is paramount for determining key correction factors in clinical dosimetry. This study sets out to provide such a parametrization based on detailed Monte Carlo simulations of clinically relevantC beams.
View Article and Find Full Text PDFManagement of Legg-Calve-Perthes disease: a scoping review with advice on initial management.
Arch Dis Child
November 2024
City St. George's University of London, London, UK
Background: Legg-Calve-Perthes disease (LCPD) is a developmental disorder causing avascular necrosis of the femoral head in children, with long-term consequences that can extend into adulthood. Early diagnosis and management in primary care are crucial but challenging.
Aim: This review aims to provide a concise overview of the presentation, differential diagnosis and management of LCPD, offering practical guidance for primary healthcare professionals.
Concise Asymmetric Total Syntheses of (+)-Dihydropleurotinic Acid and (-)-Pleurotin, Enabling Rapid Late-Stage Diversification.
JACS Au
November 2024
Laboratory of Medicinal Chemical Biology, Department of Medicinal Chemistry, College of Pharmaceutical Sciences, Soochow University, 199 Ren'ai Road, Suzhou 215123, China.
(-)-Pleurotin () and (+)-dihydropleurotinic acid () are benzoquinone meroterpenoids isolated from fungal sources with powerful antitumor and antibiotic activities. Concise asymmetric total syntheses of the stereochemically pure (+)-dihydropleurotinic acid () and (-)-pleurotin () from the chiral pool ()-Roche ester-derived vinyl bromide have been achieved in 12 and 13 longest linear steps, respectively. The key transformations feature a Michael addition/alkylation cascade reaction to forge three contiguous stereocenters matched with the natural products, a PtO-catalyzed stereoselective reduction of olefin to generate the correct stereocenter at C3, a palladium-catalyzed Negishi cross-coupling between triflate and zinc reagent to introduce the redox-sensitive para-quinone moiety, and a hydroboration/copper-catalyzed carboxylation sequence to incorporate the vital carboxyl group.
View Article and Find Full Text PDFPathogenesis and treatment of colitis-associated colorectal cancer: Insights from Traditional Chinese Medicine.
J Ethnopharmacol
February 2025
School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China. Electronic address:
Ethnopharmacological Relevance: Inflammatory Bowel Disease (IBD) is an inflammatory intestinal disease, and with prolonged illness duration, the annual risk of IBD progressing to colitis-associated colorectal cancer (CAC) gradually increases. In recent years, there has been a noticeable trend towards the application of traditional Chinese medicine (TCM) in the treatment of CAC.
Aim Of This Review: This comprehensive review summarizes the pathogenesis of CAC and details the therapeutic benefits of TCM in treating CAC, including various TCM prescriptions and ingredients, establishing the theoretical foundation for the application of TCM in CAC treatment.
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