Rhodium(ii)-fluorophore conjugates have strong rhodium-based fluorescence quenching that can be harnessed to report on a conjugate's cellular uptake and the intracellular decomposition rate. Information gleened from this study allowed the design of an improved STAT3 metalloinhibitor.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076564PMC
http://dx.doi.org/10.1039/c6cc05192hDOI Listing

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