Parallel readout of the micro-lasers facilitates effective mutual filtering of highly localized refractive index and temperature fluctuations in the analyte. Cross-referenced detection of two different types of proteins and complete chemical transducer reconfiguration is demonstrated. Selective surface functionalization of the individual lasers with high spatial accuracy is achieved by aligned microcontact stamping.
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http://dx.doi.org/10.1002/advs.201500066 | DOI Listing |
ACS Nano
January 2025
Department of Bioengineering, University of Pennsylvania, 210 S. 33rd Street, 435 Skirkanich Hall, Philadelphia, Pennsylvania 19104, United States.
Nanoparticles have gained attention as drug delivery vehicles for cancer treatment, but often struggle with poor tumor accumulation and penetration. Single external magnets can enhance magnetic nanoparticle delivery but are limited to superficial tumors due to the rapid decline in the magnetic field strength with distance. We previously showed that a 2-magnet device could extend targeting to greater tissue depths.
View Article and Find Full Text PDFNat Commun
January 2025
Empa, Swiss Federal Laboratories for Materials Science and Technology, Dübendorf, Switzerland.
Studying the self-assembly of chiral molecules in two dimensions offers insights into the fundamentals of crystallization. Using scanning tunneling microscopy, we examine an uncommon aggregation of polyaromatic chiral molecules on a silver surface. Dense packing is achieved through a chiral triangular tiling of triads, with N and N ± 1 molecules at the edges.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
January 2025
Tsinghua University, Institute of Nuclear and New Energy Technology, Room A320, Nengke Building, Qinghua Yuan No.1, Beijing, CHINA.
Exploring host-guest interactions to regulate hydrogen-bonding assembly offers a promising approach for developing advanced porous crystal materials (PCMs). However, screening compatible guests with appropriate geometries and host-guest interactions that could inhibit the dense packing of building blocks remains a primary challenge. This study presents a novel guest-induced crystallization (GIC) strategy, guided by thermodynamic calculations, to develop porous hydrogen-bonded organic frameworks (HOFs) using structurally challenging tetrazole building units.
View Article and Find Full Text PDF3D Print Addit Manuf
October 2024
Department of Mechanical Engineering, University of Massachusetts Lowell, Lowell, Massachusetts, USA.
Digital light processing (DLP) is rapidly growing in popularity as an additive manufacturing method for the fabrication of composite structures, and is an effective way to prepare high-resolution filled parts, such as ceramic green parts or composite magnets. Yet, higher solid loadings of resins and the resulting dramatic increases in viscosity limit DLP printing for applications that depend upon maximization of filler content. In this work, we investigate the capacity of a bimodal particle size distribution to enable the printing of a photosensitive resin containing up to 70 vol% of fillers.
View Article and Find Full Text PDFJ Phys Chem B
December 2024
Department of Physics, University of South Florida, Tampa, Florida 33620, United States.
Using a Lubachevsky-Stillinger-like growth algorithm combined with biased SWAP Monte Carlo and transient degrees of freedom, we generate ultradense disordered jammed ellipse packings. For all aspect ratios α, these packings exhibit significantly smaller intermediate-wavelength density fluctuations and greater local nematic order than their less-dense counterparts. The densest packings are disordered despite having packing fractions ϕ(α) that are within less than 0.
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