AI Article Synopsis

  • A woman developed a rare skin condition called neutrophilic dermatosis (ND) after taking a medicine called montelukast.
  • Neutrophilic dermatosis usually involves skin lesions that don't come from infections, and it can look different, with things like bumps or sores.
  • This case is special because it's the first time someone has shown ND with purple spots on their skin, but without a related issue called vasculitis.

Article Abstract

In this case report, we present a female patient with neutrophilic dermatosis (ND) occurring as palpable purpura after using montelukast. Neutrophilic dermatoses (NDs) are characterized by skin lesions in which mature neutrophils are predominantly located in the epidermis and dermis in the absence of any infective pathology. Classification of the NDs is based upon the recognition of clinical and pathologic features, as well as the identification of associated diseases, like Sweet's syndrome, pyoderma gangrenosum, generalized pustular psoriasis, and Behçet's disease. Cutaneous findings in NDs are variable and can include vesiculopustules, plaques, nodules, or ulcerations. Drug-induced NDs are not uncommon, but ND with palpable purpura is uncommon. The current patient appeared with a rare presentation as palpable purpura without vasculitis regarding ND. It is important that this is the first case report.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042251PMC
http://dx.doi.org/10.5152/eurjrheumatol.2014.140032DOI Listing

Publication Analysis

Top Keywords

palpable purpura
16
neutrophilic dermatosis
8
purpura montelukast
8
case report
8
case neutrophilic
4
dermatosis develop
4
palpable
4
develop palpable
4
purpura
4
montelukast case
4

Similar Publications

Polyangiitis overlap syndrome (POS) is a systemic vasculitis characterized by overlapping features of more than one well-defined vasculitic syndrome. We present the case of a 38-year-old Malay man with progressive dyspnea and palpable purpura in his lower limbs. The diagnostic evaluation revealed right-sided segmental pulmonary consolidation with pleural effusion, systolic cardiac dysfunction with the presence of an intracardiac thrombus, and left vocal cord palsy secondary to laryngeal mononeuropathy.

View Article and Find Full Text PDF

When an understanding of pathogenesis exists, skin lesions that have the appearance of blood in the skin can provide insight into the mechanisms leading to a systemic process that results in cutaneous manifestations. Of the vascular disturbances of the skin that occur in critically ill patients, some result from a non-hemorrhagic process while occurs represent bleeding into the skin. The lesions of livedo, petechiae, purpura, and ecchymoses can be approached from such a perspective.

View Article and Find Full Text PDF
Article Synopsis
  • * The study analyzed 28 patients, predominantly older adults (42.9% over 71 years), with a significant portion (53.6%) being women; previous infections were identified as triggers in 42.6% of cases, and the most common skin finding was palpable purpura (78.6%).
  • * Most patients required hospitalization (85.7%) for treatment, with an average stay of about 9.4 days,
View Article and Find Full Text PDF

Unlabelled: The aim of this study was to evaluate the cutaneous manifestations of immunoglobulin A vasculitis (IgAV) in terms of skin lesion type, distribution and persistence and to investigate the relationship between cutaneous manifestations and system involvement and treatment needs. This retrospective observational study was conducted with 489 IgAV patients who were followed-up for at least 6 months between 2013 and 2024. Demographic characteristics, detailed cutaneous manifestations, clinical findings and treatments were retrieved from electronic medical records.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!