AI Article Synopsis
- There is a gap in following international guidelines for managing metastatic colorectal cancer (CRC) in Greece and Cyprus, prompting the need for a new consensus on treatment strategies.
- An executive team from the Hellenic Society of Medical Oncology collaborated with international experts using the Delphi methodology to develop and vote on 109 statements regarding CRC management.
- The final consensus highlights the importance of a centralized approach, multidisciplinary care, adherence to guidelines, patient personalization, and that R0 resection is key for better oncological outcomes.
Article Abstract
There is discrepancy and failure to adhere to current international guidelines for the management of metastatic colorectal cancer (CRC) in hospitals in Greece and Cyprus. The aim of the present document is to provide a consensus on the multidisciplinary management of metastastic CRC, considering both special characteristics of our Healthcare System and international guidelines. Following discussion and online communication among the members of an executive team chosen by the Hellenic Society of Medical Oncology (HeSMO), a consensus for metastastic CRC disease was developed. Statements were subjected to the Delphi methodology on two voting rounds by invited multidisciplinary international experts on CRC. Statements reaching level of agreement by ≥80% were considered as having achieved large consensus, whereas statements reaching 60-80% moderate consensus. One hundred and nine statements were developed. Ninety experts voted for those statements. The median rate of abstain per statement was 18.5% (range: 0-54%). In the end of the process, all statements achieved a large consensus. The importance of centralization, care by a multidisciplinary team, adherence to guidelines, and personalization is emphasized. R0 resection is the only intervention that may offer substantial improvement in the oncological outcomes.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049546 | PMC |
| http://dx.doi.org/10.20524/aog.2016.0050 | DOI Listing |
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