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Dual miRNAs Imaging Platform Based on HRCA-Cas12a by Replacing PAM with Bubble to Reduce False Positive.
Anal Chem
January 2025
Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.
Detection and imaging of dual miRNAs based on AND logic gates can improve the accuracy of the early diagnosis of disease. However, a single target may lead to false positive. Hence, this work rationally integrates hyperbranched rolling circle amplification (HRCA) with Cas12a by replacing the PAM sequence with a bubble to sensitively detect and image miRNA-10b and miRNA-21 based on the AND logic gate.
View Article and Find Full Text PDFCombining Low-energy Images in Dual-energy Spectral CT With Deep Learning Image Reconstruction Algorithm to Improve Inferior Vena Cava Image Quality.
J Comput Assist Tomogr
January 2025
Department of Radiology, Affiliated Hospital of Shaanxi University of Chinese Medicine.
Objective: To explore the application of low-energy image in dual-energy spectral CT (DEsCT) combined with deep learning image reconstruction (DLIR) to improve inferior vena cava imaging.
Materials And Methods: Thirty patients with inferior vena cava syndrome underwent contrast-enhanced upper abdominal CT with routine dose, and the 40, 50, 60, 70, and 80 keV images in the delayed phase were first reconstructed with the ASiR-V40% algorithm. Image quality was evaluated both quantitatively [CT value, SD, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) for inferior vena cava] and qualitatively to select an optimal energy level with the best image quality.
Broadband minimalist wireless base stations without energy-consuming electrical power amplifiers are the rosy scenario of the next-generation wireless communication systems. High-power radio-over-fiber (RoF) links, which are featured by large operation bandwidths, are regarded as the supporting technology for realizing such a vision. Nevertheless, the severe signal-to-noise ratio (SNR) deterioration induced by the second Brillouin scattering in high-power and long-distance RoF links must be first solved.
View Article and Find Full Text PDFWe propose and experimentally demonstrate what we believe to be the first mid-infrared surface plasmon resonance (SPR) fiber optic sensor using a D-shaped multimode silica optical fiber coated with a 105 nm indium tin oxide (ITO) layer. The sensor shows resonance around 2700 nm, with a refractive index sensitivity of 1065.70 nm per refractive index unit (nm/RIU) for refractive indices ranging from 1.
View Article and Find Full Text PDFOrbital angular momentum (OAM), with its unique orthogonality, is widely applied in optical holographic encryption and information storage. Theoretically, the topological charge of OAM holography is infinite. However, in practice, it is restricted by the Nyquist-Shannon sampling theorem and experimental equipment, resulting in a relatively small number of practically usable channels.
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