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Optimal timing for lithium levels.
F1000Res
January 2025
Departments of Psychiatry, Neurology, Radiology, and Neuroscience, Washington University in St. Louis School of Medicine, St. Louis, MO, 63110, USA.
Reddy and Reddy (2014) discuss the optimal timing for lithium levels in patients taking once-daily extended-release lithium formulations. They argue for blood sampling 24 h after the previous dose rather than the standard 12 h. I interpret the data quite differently.
View Article and Find Full Text PDFLiquid CO-Capture Technologies: A Review.
Nanomaterials (Basel)
November 2024
College of Optoelectronic Technology, Chengdu University of Information Technology, Chengdu 610225, China.
Escalating global carbon dioxide (CO) emissions have significantly exacerbated the climate impact, necessitating imperative advancements in CO-capture technology. Liquid absorbents have received considerable attention in carbon capture for engineering applications, due to their high flexibility, reliability, and recyclability. Nonetheless, the existing technologies of liquid CO capture suffer from various issues that cannot be ignored, such as corrosion, elevated costs, and pronounced secondary pollution.
View Article and Find Full Text PDFOn the Analysis of Protein Genetic Architecture: Response to "Protein sequence landscapes are not so simple".
bioRxiv
December 2024
Department of Ecology and Evolution, University of Chicago, Chicago, IL, USA.
We recently reanalyzed 20 combinatorial mutagenesis datasets using a novel reference-free analysis (RFA) method and showed that high-order epistasis contributes negligibly to protein sequence-function relationships in every case. Dupic, Phillips, and Desai (DPD) commented on a preprint of our work. In our published paper, we addressed all the major issues they raised, but we respond directly to them here.
View Article and Find Full Text PDFThe Lambert diffuse reflection model revisited.
J Acoust Soc Am
December 2024
Department of Computer Science, Acoustics Lab, Aalto University, P.O. Box 15400, FI-00076 Aalto, Finland.
Article Synopsis
- - The Lambert diffuse reflection model is crucial for predicting sound behavior in both indoor and outdoor environments, revealing differences in reflection strength between diffusely and specularly reflecting walls.
- - Borish highlighted that a diffusely reflecting wall produces a stronger reflection (3 dB) than a specular wall when the source and receiver are aligned in a specific way, which raises questions about energy distribution.
- - The research clarifies that the difference in perceived reflection strength relates to the type of receiver used and confirms that energy conservation is upheld, providing a better understanding of the Lambert reflection model's implications.
Rifaximin discontinuation during broad-spectrum antibiotic treatment in critically ill patients with hepatic encephalopathy.
World J Hepatol
November 2024
Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, Polo Pontino, Rome 00185, Italy.
Hepatic encephalopathy (HE) is one of the main complications of cirrhosis, characterized by a wide spectrum of neuropsychiatric alterations that lead to an increase in mortality, morbidity and recurrent hospitalizations. Due to the central role in HE pathogenesis of ammonia and other neurotoxins primarily produced by the gut microbiota, the main therapeutic approaches for the treatment of HE are based on the modulation of the gut microbiota. Rifaximin is a non-absorbable broad-spectrum antibiotic, that is effective against ammonia-producing gram-positive, gram-negative, and anaerobic species, approved for the treatment of HE in secondary prophylaxis.
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