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Weight gain secondary to the use of oral Janus kinase inhibitors: A systematic review and meta-analysis.
JAAD Int
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Division of Dermatology, McMaster University, Hamilton, Canada.
Oral Janus kinase inhibitors (JAKi) are increasingly used in dermatology, rheumatology, gastroenterology, and hematology. While effective, they can cause adverse effects such as acne, nausea, cytopenia, dyslipidemia, and Herpes zoster. Recent reports have linked JAKi usage to weight changes, particularly weight gain, which can significantly impact patients' quality of life.
View Article and Find Full Text PDFHarnessing phytoconstituents in ethosomes: A new frontier in skin disorder management.
Int J Pharm
January 2025
Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India. Electronic address:
The rising incidence of skin disorders has necessitated the exploration of innovative therapeutic modalities that harness the beneficial properties of natural compounds. Phytoconstituents, renowned for their diverse pharmacological attributes, present considerable promise in the management of various dermatological conditions. This review delineates the integration of phytoconstituents into ethosomal formulations, which are advanced lipid-based carriers specifically designed to enhance transdermal delivery.
View Article and Find Full Text PDFHidradenitis Suppurativa.
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January 2025
Division of Dermatology, University College Cork, The National University of Ireland, Cork, Ireland; email:
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by the formation of nodules, abscesses, and fistulae at intertriginous sites. Pain, pruritus, malodor, and suppuration have a significant impact on quality of life for HS patients. Prevalence figures vary greatly in the literature from 0.
View Article and Find Full Text PDFReal-World Experience of Clascoterone Cream 1% in Acne Management: Case Series and Canadian Experience.
Clin Cosmet Investig Dermatol
January 2025
Western University, London, ON, Canada.
Acne vulgaris is a globally prevalent dermatological condition associated with substantial physical and psychological burden. Although acne typically presents during adolescence, it is a chronic condition that also affects many adults. Despite the spectrum of treatments available for acne, limitations in tolerability and safety concerns can present challenges for the use of conventional medications in clinical practice.
View Article and Find Full Text PDFKnowledge, Attitude, Awareness, and Practice Regarding Mites Among the Thai Population.
Patient Prefer Adherence
January 2025
Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Background: mites are common ectoparasites in humans and can cause various skin disorders known as demodicosis, ranging from nonspecific facial dermatitis to conditions resembling eczema, seborrheic dermatitis, folliculitis, and acne. Overgrowth of these mites can lead to pityriasis folliculorum, perioral dermatitis, blepharitis, and rosacea, significantly impacting skin health. This study aims to investigate the knowledge, attitude, awareness, and practice regarding mites in the Thai population and analyze the influencing factors associated with these aspects.
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