Department of Radiology, School of Medicine, Pontificia Universidad Javeriana, Bogotá D.C., Colombia.
Published: April 2016
AI Article Synopsis
Article Abstract
Over the past two decades, there has been increasing interest in the impact of oral health on cardiovascular disease, particularly regarding the effects of chronic infections such as periodontitis on the endothelium. The aim of this study was to evaluate in healthy smokers whether there are any significant differences in the frequency of endothelial dysfunction between subjects with chronic moderate to severe periodontal disease and periodontally healthy subjects. An observational cross-sectional study was conducted. The target population was adults older than 40 years of age. Blood tests were performed to determine values of CBC, glycaemia, total cholesterol, HDL-C, and LDLC. Periodontal examinations and probing were conducted with a Florida Probe®, and standardized procedures were used to measure flow-mediated dilation. Out of 150 subjects [69 male (46%) and 81 female (54%)], 75 (50%) had chronic periodontitis. The mean value for baseline flow-mediated dilation was 4.04% and the mean value for final flow-mediated dilation was 4.66%, with a 0.62% mean difference showing a statistically significant increase (p<0.001).This study found no significant difference in the flow-mediated dilation values between periodontally healthy subjects and those with periodontitis, in contrast to the literature, which suggests a negative impact of periodontal disease on endothelial function.
Background: Type 1 diabetes (T1D) carries a significant risk of atherosclerosis as the main driver for cardiovascular events. Atherosclerosis is initiated by the activation of the endothelium by various risk factors through the inflammation process. The anti-inflammatory cytokine TGF-β1 may inhibit the development of atherosclerosis.
Division of Pulmonary, Critical Care, and Sleep Medicine, College of Medicine-Jacksonville, University of Florida, 653-1 West 8th Street, L20 Jacksonville, FL 32209, USA.
Electronic cigarette (EC) is widely advertised as a safe alternative to traditional cigarette (TC). We aimed to investigate the cardiovascular effect of EC with/without nicotine compared with TC. We systematically searched PubMed/MEDLINE, EMBASE, and Cochrane CENTRAL for randomized controlled trials that compared the effect of different smoking modalities on cardiovascular function up to 1 October 2024.
Background And Aims: Herbal plants may contribute to reducing the incidence of cardiovascular disease. Yerba mate (YM) emerges as a candidate to improve endothelial function, hemodynamics, and heart rate variability (HRV) due to its antioxidant and anti-inflammatory properties, potentially decreasing cardiovascular risk. Therefore, studies are needed to assess the effect of YM ingestion on these parameters.
Vasomotor function (constriction, dilation) can be assessed ex vivo using the pressure myograph technique, also referred to as perfusion myography in older literature. The technique involves isolating an artery (or any other blood vessel/lymphatic vessel) from an animal research model or from surgery-resected human tissue. The vessel preparation is mounted between two tiny glass pipettes through which a physiological saline solution (usually Krebs') is perfused while superfusing the preparation with the same solution.
Aim: Our objective was to determine the factors associated with the successful maturation of arteriovenous fistulas during hemodialysis.
Material And Methods: This prospective study included patients treated with hemodialysis and predialysis patients. Clinical, biochemical, sociodemographic, vascular ultrasound mapping, flow-mediated dilatation, and surgical factors were analyzed.
