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Click inspired synthesis of triazole-linked vanillin glycoconjugates. | LitMetric

Click inspired synthesis of triazole-linked vanillin glycoconjugates.

Glycoconj J

Department of Chemistry, Centre of Advanced Study, Faculty of Science, Banaras Hindu University, Varanasi, -221005, India.

Published: February 2017

AI Article Synopsis

Article Abstract

The 1,3-dipolar cycloaddition of deoxy-azido sugars 1 with alkyne derivatives of p-vanillin, 3-methoxy-4-(prop-2-ynyloxy)benzaldehyde (2) and 2-methoxy-1-(prop-2-ynyloxy)-4-((prop-2-ynyloxy)methyl)benzene) (4) to afford regioselective triazole-linked vanillinglycoconjugates 5 and 6 was investigated in the presence of CuI/DIPEA in dichloromethane. All the developed glycoconjugates were characterized on the basis of IR, NMR, and MS. Graphical abstract Triazolyl vanillin glycoconjugates via click chemistry.

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Source
http://dx.doi.org/10.1007/s10719-016-9729-4DOI Listing

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