Neonatal gastrointestinal perforation in Japan: a nationwide survey.

Pediatr Surg Int

Committee of Academic Surveys and Advanced Medical Science, Japanese Society of Pediatric Surgeons, Tokyo, Japan.

Published: January 2017

AI Article Synopsis

  • This study aimed to examine the clinical features and outcomes of neonatal gastrointestinal perforation cases in Japan over the last five years.
  • A total of 536 neonates were treated, with conditions including gastric rupture, intestinal atresia, necrotizing enterocolitis, and more, resulting in an overall mortality rate of 20.5%.
  • The mortality rate for extremely low-birth-weight (ELBW) neonates was notably high at 41.1%, but it showed improvement from 62.8% in a previous survey.

Article Abstract

Purpose: The purpose of this study is to identify the current clinical features of neonatal gastrointestinal perforation in Japan.

Methods: A questionnaire about cases of neonatal gastrointestinal perforation treated in recent 5 years was sent to participating institutions of the Japanese Society of Pediatric Surgeons (JSPS).

Results: Five hundred and thirty-six neonates with gastrointestinal perforation were treated. They consisted of 42 patients with gastric rupture/perforation (GR), 33 patients with intestinal atresia/stenosis (IA), 3 patients with malrotation (ML), 118 patients with necrotizing enterocolitis (NEC), 160 patients with focal intestinal perforation (FIP), 46 patients with meconium-related ileus (MRI), 77 patients with meconium peritonitis (MP), and 57 patients with other conditions. The total mortality rate was 20.5 %. The mortality rates of the patients with GR, IA, ML, NEC, FIP, MRI, and MP were 9.5, 9.1, 0, 33.1, 20.6, 28.2, and 9.1 %, respectively. In 263 cases involving extremely low-birth-weight neonates (ELBW), 108 died (mortality rate 41.1 %). The mortality rates for ELBW with GR, NEC, FIP, MRI, MP, and other conditions were 27.3 % (3/11), 58.5 % (48/82), 21.6 % (24/111), 70.6 % (24/34), 57.1 % (4/7), and 27.8 % (5/18), respectively.

Conclusions: The mortality rates for ELBW decreased from 62.8 % in the previous survey to 41.1 % by the time of this survey.

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Source
http://dx.doi.org/10.1007/s00383-016-3985-zDOI Listing

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