Background: Fournier's gangrene (FG) is an acute progressive necrotizing fasciitis of the genital area and perineum with possible extension to the abdominal wall. Surgical debridement is the gold standard management modality of established patients. Equivocal (early) FG represents a challenge in diagnosis. The objective of this study was to compare conservative management and early exploration in cases of equivocal (early) FG.
Methods: This was an observational study where data of all patients diagnosed as early FG in our departments over 4 years (2011-2015) were enrolled. Patients were divided into two groups: group 1 with conservative treatment, and group 2 managed with urgent exploration with longitudinal hemiscrotal incision starting from external inguinal ring. All patients' demographics, vital signs, laboratory finding and clinical findings were reported.
Results: A total of 28 patients were enrolled in the study. Group 1 was managed with conservative treatment (17 patients) and group 2 underwent urgent exploration (11 patients). Overall, four patients (23.5%) out of 17 patients of group 1 showed a good response to conservative management without any surgical debridement. A total of 13 patients (76.5%) developed gangrenous discoloration and needed surgical debridement later. In group 2, four patients (36.4%) underwent scrotal exploration and release incision only without debridement and showed an excellent clinical outcome. A total of four patients (36.4%) underwent debridement with excision of doubtful deep subcutaneous and fascial tissues. The remaining three patients (27.2%) underwent debridement of necrotic fascia. The hospital stay was significantly shorter in group 2 patients than group 1 (7.5 ± 3.75 13.4 ± 5.19 days < 0.05). The mean number of debridement sessions was 3.74 ± 0.69 in group 1 1.82 ± 0.34 in group 2.
Conclusions: Early exploration and debridement in equivocal (early) FG has a better clinical outcome with reduced hospital stay and number of debridement sessions than conservative treatment with delayed debridement.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004234 | PMC |
http://dx.doi.org/10.1177/1756287216655673 | DOI Listing |
Int J Lang Commun Disord
January 2025
School of Education, Communication and Language Sciences, Newcastle University, Newcastle upon Tyne, UK.
Background: Children born with cleft palate ± lip (CP ± L) are at risk of speech sound disorder (SSD). Up to 40% continue to have SSD at age 5-6 years. These difficulties are typically described as articulatory in nature and often include cleft speech characteristics (CSC) hypothesized to result from structural differences.
View Article and Find Full Text PDFBiol Rev Camb Philos Soc
January 2025
Laboratório de Ecologia e Conservação, Departamento de Engenharia Ambiental, Universidade Federal do Paraná, Av. Cel. Francisco H. dos Santos 100, Curitiba, 81531-980, Brazil.
Non-native species can be major drivers of ecosystem alteration, especially through changes in trophic interactions. Successful non-native species have been predicted to have greater resource use efficiency relative to trophically analogous native species (the Resource Consumption Hypothesis), but rigorous evidence remains equivocal. Here, we tested this proposition quantitatively in a global meta-analysis of comparative functional response studies.
View Article and Find Full Text PDFBr Dent J
January 2025
Key Laboratory of Shaanxi Province for Craniofacial Precision Medical Research, College of Stomatology, Xi´an Jiaotong University, Xi´an, P.R. China; Department of Paediatric Dentistry, Affiliated Stomatology Hospital of Xi´an Jiaotong University, Xi´an, P.R. China.
Background Indirect pulp capping (IDPC) is a preferred treatment for pulp preservation in primary teeth. However, the survival rate of IDPC in primary teeth and impact factors is still equivocal.Aims To evaluate the survival rate of IDPC in primary teeth with a deep carious lesion approximating the pulp but without irreversible pulpitis or periapical disease.
View Article and Find Full Text PDFBMC Public Health
December 2024
Programme in Health Services and Systems Research (HSSR), Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore.
Background: Falls and fall-related injuries among older adults in Singapore are a serious health problem that require early intervention. In previous research, exercise interventions have been effective in improving functional outcomes and reducing falls for a broad group of older adults. However, results from multi-domain, multi-component falls prevention programs for high fall risk older adults in the community remain equivocal.
View Article and Find Full Text PDFJ Soc Cardiovasc Angiogr Interv
September 2024
Department of Cardiology, Baystate Medical Center, Springfield, Massachusetts.
Background: Reducing door-to-balloon (D2B) time for ST-segment elevation myocardial infarction (STEMI) has been shown to improve outcomes. Delays still occur due to various factors such as time to laboratory activation and diagnostic clarification in equivocal cases. We propose that early communication through a mobile application (app) between emergency medical services (EMS) and in-hospital providers can reduce EMS-to-balloon time and provide coordinated care to impact D2B time.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!