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Calciphylaxis in a Patient on Hemodialysis: A Case Report.
Cureus
November 2024
Cardiology, Manchester University NHS Foundation Trust, Manchester, GBR.
Article Synopsis
- Calciphylaxis is a serious condition associated with end-stage renal disease (ESRD), often occurring in patients on hemodialysis, where calcium builds up in small blood vessels causing pain and reduced blood flow.
- The disease typically affects fatty areas of the body, like the abdomen, but can appear on any skin surface, including rare locations like the genital region.
- A case study of a 53-year-old man with ESRD and painful lesions on the glans penis illustrates the quick deterioration of calciphylaxis and the challenges in treating this uncommon condition.
Relapsing Calciphylaxis of the Breast: Glucocorticoids - Friend or Foe?
Indian J Nephrol
September 2023
Department of Nephrology, St. John's Medical College Hospital, Bengaluru, Karnataka, India.
Article Synopsis
- Calciphylaxis is a rare and severe condition that causes blood vessel calcification, leading to tissue death, often appearing in areas with more body fat like the abdomen and breasts.
- An elderly woman with end-stage kidney disease experienced severe breast pain and nodules, leading to a diagnosis of calciphylaxis through clinical assessments and imaging.
- After standard treatments failed, glucocorticoids were used effectively, showing significant improvement, but she experienced a relapse after three months, requiring treatment again.
Calciphylaxis, beware the ophthalmic mimic: A case series.
Clin Nephrol Case Stud
December 2023
Department of Ophthalmology, and.
Article Synopsis
- This text discusses two rare cases of calciphylaxis that showed eye-related issues without typical skin symptoms, aiming to increase awareness of the condition.
- The cases include a 76-year-old woman with kidney failure and anterior ischemic optic neuropathy (AION), and a 44-year-old man on dialysis with AION and central retinal artery occlusion (CRAO).
- It emphasizes the importance of recognizing calciphylaxis in kidney patients with eye problems, and suggests a temporal artery biopsy for accurate diagnosis to prevent unnecessary treatments like steroids.
Calciphylaxis is an infrequent yet lethal disease often associated with end-stage kidney disease (ESKD). The most common sites include proximal and distal extremities and the trunk, with few reported in the penis and very few as gastrointestinal (GI) disease. We report a case of systemic calciphylaxis in a middle-aged male, presenting with a colostomy leak and parastomal abscess.
View Article and Find Full Text PDFIsolated Mesenteric Calciphylaxis With Ischemic Colitis in a Hemodialysis Patient Without Active Cutaneous Calciphylaxis: A Case Report of Calcific Uremic Arteriolopathy.
Kidney Med
February 2020
Renal Unit, Flinders Medical Centre, South Australia, Australia.
Calciphylaxis, also known as calcific uremic arteriolopathy, is a devastating systemic disease most commonly associated with chronic kidney failure. Its hallmark histopathologic features of small-vessel calcification, intimal hyperplasia, and microthrombi lead to microvascular occlusion and tissue necrosis. Clinically, it typically presents with painful cutaneous lesions that may be distal or proximal, with proximal lesions associated with higher mortality.
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