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A Comparative Analysis of Neurocognitive Function in Community- and Hospital-Based Patients With Schizophrenia.
Psychiatry Investig
October 2024
Department of Psychiatry and Mental Health, College of Medicine, Inha University, Incheon, Republic of Korea.
Objective: The study compared differences in various neurocognitive characteristics across treatment modalities among schizophrenia patients recruited in one city between July 2020 and June 2023 who were on regular medication.
Methods: Of the 151 participants, 113 were included in the analysis. Participants were divided into community-based and hospital-based groups, and their demographics and clinical characteristics, including insight, quality of life, positive and negative symptoms, and personal and social functioning, were examined.
Monitored and Cared for at Home? Privacy Concerns When Using Smart Home Health Technologies to Care for Older Persons.
AJOB Empir Bioeth
October 2024
Institute for Biomedical Ethics, University of Basel, Bernoullistrasse, Basel, Switzerland.
Background: States and families are facing growing challenges provide adequate care for older persons. Smart home health technologies (SHHTs) in the forms of sensor or robotic devices have been discussed as technical solutions for caregiving. Ethical and social concerns are raised with the use of such technologies for caregiving purposes, a particularly prominent one being privacy.
View Article and Find Full Text PDFHilbert-curve assisted structure embedding method.
J Cheminform
July 2024
National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, MD, 20850, USA.
Motivation: Chemical space embedding methods are widely utilized in various research settings for dimensional reduction, clustering and effective visualization. The maps generated by the embedding process can provide valuable insight to medicinal chemists in terms of the relationships between structural, physicochemical and biological properties of compounds. However, these maps are known to be difficult to interpret, and the ''landscape'' on the map is prone to ''rearrangement'' when embedding different sets of compounds.
View Article and Find Full Text PDFA pair of conjoined trinuclear sub-frameworks in a pentanuclear double-cavity discrete coordination cage.
Chem Sci
July 2024
IoE Center of Molecular Architecture, Department of Chemistry, Indian Institute of Technology Madras Chennai 600036 India
Combination of Pd(ii) with selected bis-monodentate ligands produces the familiar multinuclear Pd L type self-assembled "single-cavity discrete coordination cages" (SCDCC). If the ligand provides parallel coordination vectors, then it forms a binuclear PdL type cage, whereas utilization of ligands having appropriately divergent coordination vectors results in specific higher nuclear complexes. In contrast, preparation of emergent "multi-cavity discrete coordination cages" (MCDCC) using Pd(ii) and designer ligands is quite captivating where the neighboring cavities of the framework are conjoined with each other through a common metal center.
View Article and Find Full Text PDFThe search for meaning in health care inquiries: introducing qualitative meaning analysis.
Int J Qual Stud Health Well-being
December 2024
Department of health and care sciences, University of Gothenburg, Göteborg, Sweden.
Purpose: To describe how (QMA), based on a lifeworld theoretical approach, can be made accessible to students and researchers not well-versed in the philosophy of science or qualitative research. Additionally, to demonstrate that it is a more rigorous approach than qualitative content analysis in guiding healthcare inquiries.
Method: In recent years, qualitative approaches in nurse education and research have increasingly relied on various content analytical procedures.
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