AI Article Synopsis
- Traditional postoperative pain management has often relied on intravenous (IV) morphine for controlling pain.
- An innovative alternative is the usage of transdermal analgesics, like fentanyl, which was approved by the FDA in 2006 and uses electrical current to deliver medication through the skin.
- Studies indicate that transdermal fentanyl can either match or surpass the effectiveness of IV morphine PCA in managing postoperative pain, leading to lower pain scores and better side effects for patients.
Article Abstract
Postoperative management of pain has traditionally utilized intravenous (IV) morphine for pain control. An alternative approach to the invasive patient-controlled analgesia (PCA) system is the administration of transdermal analgesics, such as fentanyl. In 2006 the Food and Drug Administration (FDA) approved the fentanyl hydrochloride (fentanyl HCl) iontophoretic transdermal system (ITS), which utilizes iontophoretic technology to produce a controlled electrical current that propels ionized fentanyl molecules into the systemic vasculature. Transdermal fentanyl has been shown to be equivalent or superior to IV morphine PCA in a variety of postoperative settings with patients experiencing decreased pain scores and a favorable side effect profile.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037060 | PMC |
| http://dx.doi.org/10.7759/cureus.752 | DOI Listing |
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