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http://dx.doi.org/10.1111/jan.13169 | DOI Listing |
Endocr Metab Immune Disord Drug Targets
January 2025
Department of Rheumatology and Immunology, The First Affiliated Hospital of Army Medical University, Chongqing, China.
Background: Diabetes and osteoporosis, as chronic diseases with high incidence, have caused deep concern in the field of global public health due to their high morbidity and mortality. More importantly, the complex and close relationship between diabetes and osteoporosis has gradually become the focus of scientific research. It is very meaningful to carry out bibliometric analysis in the research field of diabetes and osteoporosis to describe the current international trend and present a visual representation of the past and emerging trends of diabetes and osteoporosis in the past decade.
View Article and Find Full Text PDFPopul Dev Rev
December 2024
Population Research Institute, The Pennsylvania State University, University Park, 315J Welch Building 137 Fischer Road, PA 16802, Pennsylvania, USA.
Stock estimates of the US unauthorized foreign-born population are routinely published, but less is known about this population's dynamics. Using a series of residual estimates based on 2000 Census and 2001-2022 American Community Survey (ACS), I estimate the components of change for the unauthorized immigrant population from 2000 to 2022 by region and country of origin. Further, I develop and present novel measures of expected duration in unauthorized status and demographic impact of unauthorized entries (i.
View Article and Find Full Text PDFWorld J Diabetes
January 2025
College of Traditional Chinese Medicine, Anhui University of Chinese Medicine, Hefei 230012, Anhui Province, China.
Background: Diabetes has a substantial impact on public health, highlighting the need for novel treatments. Ubiquitination, an intracellular protein modification process, is emerging as a promising strategy for regulating pathological mechanisms. We hypothesize that ubiquitination plays a critical role in the development and progression of diabetes and its complications, and that understanding these mechanisms can lead to new therapeutic approaches.
View Article and Find Full Text PDFWorld J Diabetes
January 2025
School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
Background: Epidemiological surveys indicate an increasing incidence of type 2 diabetes mellitus (T2DM) among children and adolescents worldwide. Due to rapid disease progression, severe long-term cardiorenal complications, a lack of effective treatment strategies, and substantial socioeconomic burdens, it has become an urgent public health issue that requires management and resolution. Adolescent T2DM differs from adult T2DM.
View Article and Find Full Text PDFWorld J Diabetes
January 2025
Department of Endocrinology and Metabolism, Lancashire Teaching Hospitals NHS Trust, Preston PR2 9HT, United Kingdom.
Use of immunomodulating agents to prevent the progression of autoimmune β-cell damage leading to type 1 diabetes mellitus (T1DM) is an interesting area for research. These include non-specific anti-inflammatory agents, immunologic vaccination and anti-inflammatory agents targeting specific immune cells or cytokines. Teplizumab is an anti-CD3-molecule that binds to and leads to the disappearance of the CD3/TCR complex and rendering the T cell anergic to its target antigen.
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