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Minimally invasive biomarkers for triaging lung nodules-challenges and future perspectives.
Cancer Metastasis Rev
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CT chest scans are commonly performed worldwide, either in routine clinical practice for a wide range of indications or as part of lung cancer screening programs. Many of these scans detect lung nodules, which are small, rounded opacities measuring 8-30 mm. While the concern about nodules is that they may represent early lung cancer, in screening programs, only 1% of such nodules turn out to be cancer.
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Department of Plant Science, McGill University, Macdonald Campus, 21111 Rue Lakeshore, Ste-Anne-de-Bellevue, H9X 3V9, Québec, Canada.
New crop`s need to emerge to provide sustainable solutions to climate change and increasing abiotic and biotic constraints on agriculture. A large breadth of northern fruit trees and shrubs exhibit a high potential for domestication; however, obstacles to implementing traditional breeding methods have hampered or dissuaded efforts for improvement. This review article proposes a unique roadmap for domestication of northern fruit crops, with a focus on biotechnological (e.
View Article and Find Full Text PDFChromosome-level genome assembly and characterization of Kaixuan 016: A high-oleic peanut variety with improved agronomic traits developed through gamma-radiation-assisted breeding.
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Shennong Laboratory/ Henan Academy of Crop Molecular Breeding, Henan Academy of Agricultural Sciences/Henan Provincial Key Laboratory for Oil Crops Improvement, Zhengzhou 450002, China. Electronic address:
High-oleic peanuts are increasingly valued in agricultural production and consumer markets. Nevertheless, limited genomic information hinders the integration of genetic analyses and modern breeding strategies. This study details a chromosome-level genome assembly of Kaixuan 016, a high-oleic peanut variety developed through gamma-radiation-assisted breeding, exhibiting enhanced agronomic traits.
View Article and Find Full Text PDFA multi-scale cognitive interaction model of instrument operations at the Linac Coherent Light Source.
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View Article and Find Full Text PDFCell-Free Systems to Mimic and Expand Metabolism.
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Department of Biochemistry and Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, 35043 Marburg, Germany.
Cell-free synthetic biology incorporates purified components and/or crude cell extracts to carry out metabolic and genetic programs. While protein synthesis has historically been the primary focus, more metabolism researchers are now turning toward cell-free systems either to prototype pathways for cellular implementation or to design new-to-nature reaction networks that incorporate environmentally relevant substrates or new energy sources. The ability to design, build, and test enzyme combinations has accelerated efforts to understand metabolic bottlenecks and engineer high-yielding pathways.
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