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Background: Infertility is a special reproductive health defect. For women, congenital uterine malformations, extensive adhesions in the uterine cavity, and hysterectomy are associated with infertility. Uterine transplantation is technically feasible, but its clinical application and development are limited by donor shortages and immune rejection.

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Article Synopsis
  • Placenta previa is a serious condition where the placenta partially or completely covers the cervix, increasing the risk of postpartum hemorrhage (PPH) and complications for both mother and baby.* -
  • A 36-year-old woman with a complicated medical history, including chronic hypertension and prior cesarean sections, experienced massive PPH during a scheduled cesarean due to complete placenta previa.* -
  • Due to the patient's refusal of blood transfusions as a Jehovah's Witness, her treatment for PPH involved urgent interventions, including uterine artery embolization and ultimately a hysterectomy after other methods failed.*
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Endometrioid tubal intraepithelial neoplasia (E-TIN): case report & literature review.

J Mol Histol

November 2024

Department of Histopathology and Cytopathology, Cotman Centre, Norfolk and Norwich University Hospital, Colney Lane, Norwich, NR4 7UB, UK.

An endometrioid carcinogenic pathway of the fallopian tube with possible potential precursors including type II SCOUTs (secretory cell outgrowths) and E-TIN (endometrioid tubal intraepithelial neoplasia) has been recently documented. We report an incidental focus of E-TIN identified in a hysterectomy specimen for Grade 1 endometrioid type endometrial carcinoma. The lesion was present at the fimbriated end of left fallopian tube involving 1 plica.

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This review focuses on uterine mesenchymal tumors that are defined on a molecular level by a single and unique genetic alteration, that is somehow necessary and sufficient to allow tumor growth and progression. Although diverse from a clinical, morphological and immunohistochemical point of view, the different entities we are going to talk about share both a simple genomic profile with a low number of chromosomal alterations observed by CGH Array (few deletions, gains or amplifications..

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