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Article Synopsis
  • A study conducted in Addis Ababa, Ethiopia aimed to establish reference intervals (RIs) for serum protein electrophoresis in healthy adults, as existing data is scarce in resource-limited countries.
  • The research included 297 adults and utilized statistical methods to analyze serum samples collected from various sub-cities, applying guidelines for reference range establishment.
  • The findings showed specific RIs for different serum proteins, revealing gender differences, particularly in albumin and globulin levels, while beta-2 and gamma globulin showed no significant gender variation.
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Lung cancer is the leading cause of cancer-related deaths in the United States. Several anaplastic lymphoma kinase (ALK) rearrangement inhibitors have been approved for the treatment of metastatic ALK-positive non-small cell lung cancer (NSCLC). Effective disease management requires an understanding of how these treatments are used in clinical practice, since low treatment adherence and/or early discontinuation have been associated with poor patient outcomes.

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Background: Cultural safety encourages practitioners to examine how their own culture shapes their clinical practice and to respect their patients' worldviews. Lack of cultural safety in health care is linked to stigma and discrimination toward culturally diverse patients. Training in cultural safety poses considerable challenges.

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Aims: To review the effectiveness of the revised Vienna classification (rVC) at predicting histological outcome and defining the postendoscopic resection (ER) clinical management plan of gastro-oesophageal dysplasia and early neoplasia in a UK tertiary-centre population.

Methods: This was a retrospective cohort study between November 2011 and May 2018. 157 patients from Salford Royal NHS Foundation Trust in the UK were included.

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