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Safety of flow-controlled ventilation with positive and negative end-expiratory pressure in a swine model of intracranial hypertension.
Intensive Care Med Exp
December 2024
Division of Intensive Care, Department of Anaesthesiology, Pharmacology, Intensive Care and Emergency Medicine, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, Geneva, Switzerland.
Background: Patients with brain damage often require mechanical ventilation. Although lung-protective ventilation is recommended, the application of increased positive end-expiratory pressure (PEEP) has been associated with elevated intracranial pressure (ICP) due to altered cerebral venous return. This study investigates the effects of flow-controlled ventilation (FCV) using negative end-expiratory pressures (NEEP), on cerebral hemodynamics in a swine model of intracranial hypertension.
View Article and Find Full Text PDFMeeting report of the 57th Annual Meeting of the Japanese Society for Developmental Biologists.
Dev Growth Differ
September 2024
Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
The 57th Annual Meeting of the Japanese Society for Developmental Biologists was held at Miyako Messe and ROHM Theater Kyoto from June 19 to 22, 2024. After the COVID-19 pandemic, this was the first meeting where all restrictions were removed. This year's theme was "Breaking Through Boundaries.
View Article and Find Full Text PDFThe 36th International Mammalian Genome Conference (IMGC) was held in a hybrid format at the Tsukuba International Congress Center in Tsukuba, Ibaraki, Japan, for 4 days from March 28 to 31, 2023. This international conference on functional genomics of mouse, human, and other mammalian species attracted 246 participants in total, of which 129 were from outside Japan, including Europe, the United States and Asia, and 117 participants were from Japan. The conference included three technical workshops, keynote lectures by domestic researchers, commemorative lectures for the conference awards, 57 oral presentations, and 97 poster presentations.
View Article and Find Full Text PDFComparison of Sales From Vending Machines With 4 Different Food and Beverage Messages: A Randomized Trial.
JAMA Netw Open
May 2024
Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia.
Importance: Point-of-sale food messaging can encourage healthier purchases, but no studies have directly compared multiple interventions in the field.
Objective: To examine which of 4 food and beverage messages would increase healthier vending machine purchases.
Design, Setting, And Participants: This randomized trial assessed 13 months (February 1, 2019, to February 29, 2020) of vending sales data from 267 machines and 1065 customer purchase assessments from vending machines on government property in Philadelphia, Pennsylvania.
Associations of the Gut Microbiome With Treatment Resistance in Schizophrenia.
JAMA Psychiatry
March 2024
Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.
Importance: There is growing interest in the role of gut microbiome composition in schizophrenia. However, lifestyle factors are often neglected, and few studies have investigated microbiome composition in treatment-resistant schizophrenia.
Objective: To explore associations between the gut microbiome and schizophrenia diagnosis, treatment resistance, clozapine response, and treatment-related adverse effects while adjusting for demographic and lifestyle factors.
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