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Esophageal Cancer-Related Gene-4 Contributes to Lipopolysaccharide-Induced Ion Channel Dysfunction in hiPSC-Derived Cardiomyocytes.
J Inflamm Res
December 2024
Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Department of Cardiology, The Affiliated Hospital, Southwest Medical University, Luzhou, People's Republic of China.
Background And Purpose: Esophageal cancer-related gene-4 (ECRG4) participate in inflammation process and can interact with the innate immunity complex TLR4-MD2-CD14 on human granulocytes. In addition, ECRG4 participate in modulation of ion channel function and electrical activity of cardiomyocytes. However, the exact mechanism is unknown.
View Article and Find Full Text PDFDiffering Content and Language Based on Poster-Patient Relationships on the Chinese Social Media Platform Weibo: Text Classification, Sentiment Analysis, and Topic Modeling of Posts on Breast Cancer.
JMIR Cancer
May 2024
Graduate School of Science and Technology, Nara Institute of Science and Technology, Ikoma, Japan.
Background: Breast cancer affects the lives of not only those diagnosed but also the people around them. Many of those affected share their experiences on social media. However, these narratives may differ according to who the poster is and what their relationship with the patient is; a patient posting about their experiences may post different content from someone whose friends or family has breast cancer.
View Article and Find Full Text PDF"More than a song and dance": Exploration of patient perspectives and educational quality of gynecologic cancer content on TikTok.
Gynecol Oncol
August 2023
Division of Gynecologic Oncology, The Ohio State University Wexner Medical Center, The James Cancer Hospital and Solove Research Institute, Starling Loving Hall, M210, 320 W. 10th Avenue, Columbus, OH 43210, USA.
Objective: To investigate themes, quality, and reliability of gynecologic cancer-related content on the social media application TikTok.
Methods: TikTok was systematically searched for the 100 most popular posts for ovarian cancer (OC), endometrial cancer (EC), cervical cancer (CC), vulvar cancer (VC), and gestational trophoblastic disease (GTD) in August 2022. Data was collected for demographics, tone, and themes.
Real-world adherence and persistence with anaplastic lymphoma kinase inhibitors in non-small cell lung cancer.
J Manag Care Spec Pharm
March 2022
Genentech Inc., South San Francisco, CA.
Lung cancer is the leading cause of cancer-related deaths in the United States. Several anaplastic lymphoma kinase (ALK) rearrangement inhibitors have been approved for the treatment of metastatic ALK-positive non-small cell lung cancer (NSCLC). Effective disease management requires an understanding of how these treatments are used in clinical practice, since low treatment adherence and/or early discontinuation have been associated with poor patient outcomes.
View Article and Find Full Text PDFWhen Engagement Leads to Action: Understanding the Impact of Cancer (Mis)information among Latino/a Facebook Users.
Health Commun
August 2022
Department of Health, Behavior & Society, Johns Hopkins School of Public Health.
Latinos/as - the largest minority group in the U.S. - are avid Facebook users, making this an opportune tool to educate on the uptake of cancer prevention and screening behaviors.
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