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A Case of Aquagenic Syringeal Acrokeratoderma in a Male Patient Undergoing Treatment With an Angiotensin-Converting Enzyme Inhibitor.
Cureus
November 2024
Internal Medicine, Kettering Health Network, Kettering, USA.
Aquagenic syringeal acrokeratoderma (ASA) is a rare dermatological condition characterized by the transient appearance of edematous, white, translucent papules on the palms following water exposure. While the condition is most commonly associated with cystic fibrosis (CF) and predominantly affects young women, this report presents a unique case in a 24-year-old man without a history of cystic fibrosis. The patient reported a 10-month history of painful, pruritic eruptions on the hands following exposure to water.
View Article and Find Full Text PDFA case of aquagenic wrinkling of the palms triggered by isotretinoin.
Ital J Dermatol Venerol
October 2024
Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Response to Hill et al, "Digital clubbing in cystic fibrosis: The nails as clues to advanced disease".
J Am Acad Dermatol
November 2024
Department of Dermatology, University of Virginia, Charlottesville, Virginia.
Wood's light as a noval diagnostic tool in aquagenic keratoderma.
Skin Health Dis
June 2024
Dermatology Prince Mohammed Medical City AlJowf Saudi Arabia.
Article Synopsis
- Aquagenic keratoderma is a rare skin condition that causes wrinkling and translucent papules on the palms and occasionally the soles when exposed to water.
- It is commonly seen in patients with cystic fibrosis or those who are carriers of the cystic fibrosis gene, with an estimated occurrence of up to 41% in that population.
- The paper discusses a novel approach using Wood's light as a diagnostic tool for aquagenic keratoderma, marking the first reported case of its application in this context.
ECFS standards of care on CFTR-related disorders: Identification and care of the disorders.
J Cyst Fibros
July 2024
IRCCS Istituto Giannina Gaslini, Cystic Fibrosis Center, Genoa, Italy.
This is the third paper in the series providing updated information and recommendations for people with cystic fibrosis transmembrane conductance regulator (CFTR)-related disorder (CFTR-RD). This paper covers the individual disorders, including the established conditions - congenital absence of the vas deferens (CAVD), diffuse bronchiectasis and chronic or acute recurrent pancreatitis - and also other conditions which might be considered a CFTR-RD, including allergic bronchopulmonary aspergillosis, chronic rhinosinusitis, primary sclerosing cholangitis and aquagenic wrinkling. The CFTR functional and genetic evidence in support of the condition being a CFTR-RD are discussed and guidance for reaching the diagnosis, including alternative conditions to consider and management recommendations, is provided.
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