Asymptomatic Effluent Protozoa Colonization in Peritoneal Dialysis Patients.

Perit Dial Int

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Porto, Portugal Faculdade de Medicina Dentária, Universidade do Porto, Porto, Portugal

Published: December 2017

Currently, chronic kidney disease (CKD) is a global health problem. Considering the impaired immunity of CKD patients, the relevance of infection in peritoneal dialysis (PD), and the increased prevalence of parasites in CKD patients, protozoa colonization was evaluated in PD effluent from CKD patients undergoing PD. Overnight PD effluent was obtained from 49 asymptomatic stable PD patients. Protozoa analysis was performed microscopically by searching cysts and trophozoites in direct wet mount of PD effluent and after staining smears. Protozoa were found in PD effluent of 10.2% of evaluated PD patients, namely Blastocystis hominis, in 2 patients, and Entamoeba sp., Giardia sp., and Endolimax nana in the other 3 patients, respectively. None of these patients presented clinical signs or symptoms of peritonitis at the time of protozoa screening. Our results demonstrate that PD effluent may be susceptible to asymptomatic protozoa colonization. The clinical impact of this finding should be further investigated.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033635PMC
http://dx.doi.org/10.3747/pdi.2015.00226DOI Listing

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