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Overview of Available Treatments and Their Limitations for Hypertrophic Facet Joints-A Systematic Review of the Literature.
J Am Acad Orthop Surg Glob Res Rev
January 2025
Universidad Autónoma de Guadalajara, School of Medicine, Zapopan, Mexico.
Background: Physicians worldwide face the challenging task of improving patient satisfaction by reducing pain in injured patients. Currently, available therapeutic approaches provide only short-term relief of symptoms without addressing long-term satisfaction. This has led to exploring regenerative treatment options that can deliver better outcomes.
View Article and Find Full Text PDFMacrophage membrane-biomimetic ROS-responsive platinum nanozyme clusters for acute kidney injury treatment.
Biomaterials
December 2024
Department of Biotherapy and Department of Hematology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China. Electronic address:
Acute kidney injury (AKI) is a common clinical syndrome characterized by the rapid loss of renal filtration function. No standard therapeutic agent option is currently available. The development and progression of AKI is a continuous and dynamical pathological process.
View Article and Find Full Text PDFDimensions of bony Kambin's triangle pertaining to endoscopic procedure.
Med J Armed Forces India
December 2024
Senior Consultant (Neurology), NH MMI Superspeciality, Raipur, Chhattisgarh, India.
Background: Endoscopic procedures nowadays are successful, minimally invasive, and safer, with fewer intraoperative and postoperative complications and shorter hospital stays. Kambin's triangle (KT) is the three-dimensional configuration that is used as a transforaminal anatomical corridor for epidural steroid injections and endoscopic surgeries for various lumbar pathologies. This study aims to estimate the dimensions of KT and diameter of the cannula for the transforaminal surgical approaches using KT in the Chhattisgarh population.
View Article and Find Full Text PDFEscalating Growth to Rapid Decline of Utilization Patterns of Facet Joint Interventions in Managing Spinal Pain in the Medicare Population: Updated Analysis of the Effect of Multiple Factors from 2000 To 2022.
Pain Physician
December 2024
Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Background: The use of facet joint interventions for spinal pain management experienced rapid growth between 2000 and 2010, with an annual increase of 14.2%. However, this trend slowed significantly from 2010 to 2019, with a reduced growth rate of just 2.
View Article and Find Full Text PDFA systematic review of microneedles technology in drug delivery through a bibliometric and patent overview.
Heliyon
December 2024
Materias Srl, Corso N. Protopisani 50, 80146, Naples, Italy.
The transdermal drug delivery (TDD) route has gathered considerable attention for its potential to improve therapeutic efficacy while minimizing systemic side effects. Among transdermal technologies, microneedle (MN) devices have proven to be a promising approach that combines the advantages of traditional needle injections and non-invasive topical applications. This review provides a comprehensive analysis of progress in transdermal drug delivery systems (TDDS) via MN from 2000 to 2023, integrating bibliometric analysis and patent landscape to present a multi-faceted perspective on the evolution of this technology.
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