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| http://dx.doi.org/10.3389/fnins.2016.00395 | DOI Listing |
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Trans-Vessel Wall Cell Transplantation, Engraftment, and Tumor Access in the VX2 Rabbit Model.
Cell Transplant
January 2025
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
The trans-vessel wall device (TW-device) is a new endovascular tool for precise and safe delivery of various payloads (cells, viral, modified RNA, chemotherapy, growth factors) in oncology and regenerative medicine. The twofold aim of this study was to assess cell engraftment and tumor growth using the TW-device for endovascular transplantation and to evaluate its ability to directly access solid tumors. We used the VX2 model in the rabbit kidney to compare percutaneously implanted fresh VX2 cells with TW-device injections of cryopreserved VX2 cells.
View Article and Find Full Text PDFCase report: Treatable immune-mediated severe orthostatic hypotension in SARS-CoV-2 infection.
Front Neurosci
January 2025
Service of Neurology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.
We report a patient with autonomic dysfunction following acute SARS-CoV-2 infection, presenting progressively worsening severe orthostatic hypotension to the point where she could no longer sit or stand. The patient experienced a delay in diagnosis after an initial misdiagnosis of a functional neurological disorder. Persistent orthostatic symptoms prompted us to re-examine the diagnosis and explore other diagnostic tools, which ultimately allowed us to identify and treat severe immune-mediated orthostatic hypotension (OH).
View Article and Find Full Text PDFIt's Hard to Prepare for Task Novelty: Cueing the Novelty of Upcoming Tasks Does Not Facilitate Task Performance.
J Cogn
January 2025
Department of Experimental Psychology, Ghent University, Henri Dunantlaan 2, 9000 Ghent, Belgium.
Rapidly learning new tasks, such as using new technology or playing a new game, is ubiquitous in our daily lives. Previous studies suggest that our brain relies on different networks for rapid task learning versus retrieving known tasks from memory, and behavioral studies have shown that novel versus practiced tasks may rely on different task configuration processes. Here, we investigated whether explicitly informing about the novelty of an incoming task would help participants prepare for different task configuration processes, such as pre-adjusting working memory gating functions.
View Article and Find Full Text PDFOptimising diagnostics for hard-of-hearing infants: factors associated with successful MRI scanning without general anaesthesia.
Eur Arch Otorhinolaryngol
January 2025
Otolaryngology - Head and Neck Surgery, section Ear & Hearing, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, 1081 HV, The Netherlands.
Purpose: Scanning during infancy is often required in otology, preferably without general anaesthesia. This study aims to determine the success rate of MRI of the head without general anaesthesia for infants, and to identify predictors for a successful scan.
Methods: Data was extracted from the electronic patient file for patients who received MRI of the head without general anaesthesia between 01-01-2019 and 31-12-2022 at an age younger than 6 months.
Self-inflicted oral-dental mutilations (SIODMs) in paediatric patients: a systematic review of case reports and case series.
Eur J Paediatr Dent
January 2025
Dentistry Unit, AORN Santobono-Pausilipon Pediatric Hospital, 80129 Naples, Italy.
Aim: Self-inflicted oral-dental mutilations (SIODMs) are the result of an intentional or unintentional action that leads to anatomical and functional damage to the soft and hard tissues of the oral cavity. In paediatric patients they can be associated with both organic and functional diseases. A systematic review was conducted aiming to consolidate and integrate the existing knowledge on SIODM in paediatric patients.
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