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Maintaining balance while simultaneously performing other tasks is common during everyday activities. However, this dual-tasking (DT) divides attention and increases cognitive demand, which can be detrimental to stability in older adults. It is unknown if the focus of attention influences how a dual-task affects balance and whether this is detectable in middle-aged adults.

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Biomechanical analysis of step-up and step-down tasks in knee osteoarthritis: Insights from leading and trailing limbs.

Clin Biomech (Bristol)

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Rehabilitation Research Institute of Singapore, Nanyang Technological University, 11 Mandalay Rd, #14-03 Clinical Sciences Building, 308232, Singapore; Department of Orthopaedic Surgery, Woodlands Health, National Healthcare Group, 737628, Singapore.

Background: Stair climbing tests are pivotal when assessing physical performance in knee osteoarthritis patients, yet the biomechanical strategies that underpin poor stair climbing ability are heterogeneously reported. Single step tasks emulate a step-by-step gait pattern, an approach associated with knee pain when stair climbing. The objective of this study is to analyse the biomechanics and electromyography activity of both the leading and trailing limbs during single Step-up and Down tasks in knee osteoarthritis patients.

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Bimetallic metal-organic frameworks as electrode modifiers for enhanced electrochemical sensing of chloramphenicol.

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Key Laboratory of Optoelectronic Chemical Materials and Devices of Ministry of Education, College of Optoelectronic Materials and Technology, Jianghan University, Wuhan, 430056, China.

An electrochemical sensor is presented for the detection of the chloramphenicol (CAP) based on a bimetallic MIL-101(Fe/Co) MOF electrocatalyst. The MIL-101(Fe/Co) was prepared by utilizing mixed-valence Fe (III) and Co (II) as metal nodes and terephthalic acid as ligands with a simple hydrothermal method and characterized by SEM, TEM, XRD, FTIR, and XPS. Electrochemical measurements such as electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), and differential pulse voltammetry (DPV) showed that bimetallic MIL-101(Fe/Co) had the faster electron transfer, larger electroactive area, and higher electrocatalytic activity compared with  their monometallic counterparts due to the strong synergistic effect between bimetals.

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Zero echo time (zero-TE) pulse sequences provide a quiet and artifact-free alternative to conventional functional magnetic resonance imaging (fMRI) pulse sequences. The fast readouts (<1 ms) utilized in zero-TE fMRI produce an image contrast with negligible contributions from blood oxygenation level-dependent (BOLD) mechanisms, yet the zero-TE contrast is highly sensitive to brain function. However, the precise relationship between the zero-TE contrast and neuronal activity has not been determined.

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Unlabelled: Stroke patients are rarely asked about their responses to specific design attributes. Virtual reality (VR) offers a promising tool to explore how hospital environments are experienced after stroke.

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