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Effect of psilocybin versus escitalopram on depression symptom severity in patients with moderate-to-severe major depressive disorder: observational 6-month follow-up of a phase 2, double-blind, randomised, controlled trial.
EClinicalMedicine
October 2024
Centre for Psychedelic Research, Division of Psychiatry, Department Brain Sciences, Imperial College London, United Kingdom.
Background: Psilocybin therapy (PT) produces rapid and persistent antidepressant effects in major depressive disorder (MDD). However, the long-term effects of PT have never been compared with gold-standard treatments for MDD such as pharmacotherapy or psychotherapy alone or in combination.
Methods: This is a 6-month follow-up study of a phase 2, double-blind, randomised, controlled trial involving patients with moderate-to-severe MDD.
Endovascular treatment of postoperative aortic coarctation aneurysms-a single center experience.
Front Cardiovasc Med
December 2024
Department of Cardiology, University Hospital 'St. Ekaterina', Medical University of Sofia, Sofia, Bulgaria.
Background: Formation of local type aortic aneurysm years after surgical repair of coarctation (CoA) occurs in 10% of patients independent of the surgical technique and is a potentially life-threatening condition if left untreated with a high risk of aortic rupture. Redo open surgery is associated with 14% in-hospital mortality and a high risk of complications. Endovascular treatment appears to be a feasible alternative with a high success rate and low morbidity and mortality, but data concerning long-term results is still mandatory.
View Article and Find Full Text PDFCatheter-Directed Aspiration for Right Atrial and Right Ventricular Masses: Trends in Use Over the Years and Comparison Between Percutaneous and Surgical Thrombectomy for Clot in Transit.
Catheter Cardiovasc Interv
January 2025
John H. Stroger Jr. Hospital of Cook County, Chicago, Illinois, USA.
Background: Percutaneous mechanical aspiration thrombectomy is increasingly being employed as a less invasive alternative for managing right heart masses, including clot in transit.
Aims: We aimed to analyze trends in the use of catheter-directed aspiration (CDA) for right heart masses. Additionally, we analyzed in-hospital outcomes of percutaneous versus surgical approaches for patients with CIT and PE.
Exploring voice barriers and subsequent practices among frontline healthcare workers in Pakistan: a comprehensive mixed-methods analysis.
BMC Health Serv Res
January 2025
Department of Doctor of Physiotherapy, Riphah International University, Islamabad, Pakistan.
Background: Voice barriers among frontline healthcare workers hinder safety related to work and patients. Understanding these barriers and practices is crucial to improve voice behavior in healthcare settings. Therefore, this study aims to identify the voice barriers and practices among healthcare workers in Pakistan.
View Article and Find Full Text PDFImpacts of a puberty and period education intervention among 9- to 12-year-old girls in the New York metropolitan area: a randomized trial.
BMC Public Health
January 2025
Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY, 10032, USA.
Objectives: To evaluate the immediate impacts of an illustrated book on puberty and periods for girls in the United States (US).
Methods: We conducted a randomized educational intervention between February-May 2023 among girls ages 9-12 years in after-school programs in the New York metropolitan area (n = 123). Girls were assigned to read a book on puberty and periods or an alternative book on healthy eating.
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