Design of specific kinase inhibitors is an appealing approach for developing new anticancer treatments. However, only a few success stories have been reported to date. Here we demonstrate how the combination of old-fashioned and new biophysical tools together with recent advances in genomics and molecular evolution can aid in overcoming existing limitations.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972104 | PMC |
| http://dx.doi.org/10.1080/23723556.2015.1046580 | DOI Listing |
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