Telomerase Regulation from Beginning to the End.

Genes (Basel)

Bloomfield Centre for Research in Aging, Lady Davis Institute for Medical Research, Jewish General Hospital, 3755 Côte Ste-Catherine Road, Montréal, QC H3T 1E2, Canada.

Published: September 2016

The vast body of literature regarding human telomere maintenance is a true testament to the importance of understanding telomere regulation in both normal and diseased states. In this review, our goal was simple: tell the telomerase story from the biogenesis of its parts to its maturity as a complex and function at its site of action, emphasizing new developments and how they contribute to the foundational knowledge of telomerase and telomere biology.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042394PMC
http://dx.doi.org/10.3390/genes7090064DOI Listing

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