Objective: To document the neonatal outcomes of preterm birth in twin pregnancies and to investigate whether perinatal and obstetric parameters are associated with clinical outcomes.
Methods: This retrospective trial was conducted on data gathered from 176 preterm twins delivered in the obstetrics and gynecology department of our tertiary care center. Data extracted from medical files of 88 pregnant women who gave preterm birth (at 26(0/7) to 36(6/7) gestational weeks) to twins were analyzed. Maternal/fetal descriptive and obstetric parameters, sonographic data, route of delivery, indication for cesarean section, birth weight, Apgar scores, head circumference, umbilical cord length and placental weight were noted.
Results: The average age of the pregnant women was 28.8±6.4 years and ultrasonographic gestational age was 31.9±2.6 weeks. Apgar scores at 1(st) minute were affected significantly by fetal body weight (p=0.001), gestational age (p=0.001), height (p=0.004) and head circumference (p=0.011). None of these variables exhibited a noteworthy effect on Apgar scores at 5(th) minute.
Conclusion: Efforts must be made to achieve advancement of gestational age until delivery in the follow-up preterm of twins. A well-established algorithm with special emphasis to risk factors is necessary to standardize and popularize the appropriate management strategy.
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http://dx.doi.org/10.12669/pjms.324.10409 | DOI Listing |
Hum Reprod
December 2024
Assisted Reproduction Center, Northwest Women's and Children's Hospital, Xi'an, China.
Study Question: Are live birth rates (LBRs) per woman following flexible progestin-primed ovarian stimulation (fPPOS) treatment non-inferior to LBRs per woman following the conventional GnRH-antagonist protocol in expected suboptimal responders undergoing freeze-all cycles in assisted reproduction treatment?
Summary Answer: In women expected to have a suboptimal response, the 12-month likelihood of live birth with the fPPOS treatment did not achieve the non-inferiority criteria when compared to the standard GnRH antagonist protocol for IVF/ICSI treatment with a freeze-all strategy.
What Is Known Already: The standard PPOS protocol is effective for ovarian stimulation, where medroxyprogesterone acetate (MPA) is conventionally administered in the early follicular phase for ovulatory suppression. Recent retrospective cohort studies on donor cycles have shown the potential to prevent premature ovulation and maintain oocyte yields by delaying the administration of MPA until the midcycle (referred to as fPPOS), similar to GnRH antagonist injections.
PLoS One
December 2024
Department of Nursing, College of Medicine and Health Science, Woldia University, Woldia, Ethiopia.
Introduction: An unintended pregnancy refers to a situation where a pregnancy occurs either when there is no desire for a child (unwanted) or when it takes place at a time that was not anticipated (mistimed). Pregnant women infected with HIV face a two to tenfold increased risk of mortality during both pregnancy and the postpartum period compared to those who are not infected. A national level cohort study has identified that about 70 babies born HIV positive, 60% of them were from unplanned pregnancy.
View Article and Find Full Text PDFVestn Otorinolaringol
December 2024
Mendeleev Russian University of Chemical Technology, Moscow, Russia.
A group of Russian specialists dealing with the problems of auditory function in premature babies touches upon important issues of early detection of hearing loss and deafness in this contingent of children born before the date of physiological birth. The purpose of the article was to argue the need for a personalized approach to the diagnosis of auditory function in premature and full-term babies depending on the timing of gestation and their somatic state at the time of birth, as well as the comprehensive rehabilitation of children with hearing loss and deafness. The article describes the advantages of the previously developed computer program Multiplicity of audiological monitoring in children of the first year of life with risk factors for hearing loss and deafness.
View Article and Find Full Text PDFVestn Otorinolaringol
December 2024
Pirogov Russian National Research Medical University, Moscow, Russia.
Unlabelled: The acoustic reflex is a physiological protective mechanism of the sound-conducting system of the auditory analyzer, which allows to identify various retrocochlear lesions of the human auditory system. The absence of its registration may indicate both pathology and immaturity of the auditory analyzer in children of the first year of life.
Objective: To register the acoustic reflex in children of the first year of life, to identify a full-fledged acoustic reflex at various frequencies and to analyze the dependence of its appearance on the timing of gestation.
Dent J (Basel)
December 2024
Section of Preventive and Pediatric Dentistry, Department of Orthodontics, Jena University Hospital, 07743 Jena, Germany.
Along with the long-term sequelae of preterm birth for general health, oral health is potentially influenced by prematurity due to developmental and behavioral peculiarities. This study aimed to compare oral health parameters in the mixed dentition of prematurely and full-term born children. Dental caries, developmental defects of enamel (DDE), and gingival inflammation were assessed in 7-to-9-year-old children ( = 38) born preterm (PT) compared to a matched control group born full-term (FT) in Germany.
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