Sixty infants with transposition of the great arteries and intact ventricular septum underwent primary surgical correction in the first 3 months of life. Twenty-three patients had a Mustard procedure (group 1) and 37 patients, an arterial switch operation (group 2). The mean age at the time of repair was 42 +/- 31 days for group 1 and 8 +/- 6 days for group 2 (p less than 0.001). The mean weight at the time of repair was 3.6 +/- 0.7 kg for group 1 and 3.4 +/- 0.5 kg for group 2 (p = not significant). Operative mortality was 8.7% (2/23) in group 1 and 8.1% (3/37) in group 2 (p = not significant). The incidence of arrhythmias in the early postoperative period was 39% (9/23) in group 1 and 11% (4/37) in group 2 (p less than 0.01). All patients were followed a mean of 4.8 +/- 2.4 years in group 1 and 2.6 +/- 1.4 years in group 2 (p less than 0.001). Postoperative catheterization has been performed in 86% (18/21) of group 1 operative survivors and 50% (17/34) of group 2 operative survivors. Ejection fraction of the systemic ventricle was 79% +/- 15% of predicted normal in group 1 and 98% +/- 6% in group 2 (p less than 0.005). The incidence of late arrhythmias was 57% (12/21) in group 1 and 3% (1/34) in group 2 (p less than 0.001). There have been 2 late deaths in group 1 and 1 late death in group 2 (p = not significant).(ABSTRACT TRUNCATED AT 250 WORDS)

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http://dx.doi.org/10.1016/0003-4975(89)90168-9DOI Listing

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