Shrimp fisheries along the Brazilian coast have significant environmental impact due to high by-catch rates (21 kg per kilogram of shrimp). Typically discarded, by-catch contains many invertebrates that may host a great variety of bacterial genera, some of which may produce bioactive natural products with biotechnological applications. Therefore, to utilize by-catch that is usually discarded we explored the biotechnological potential of culturable bacteria of two abundant by-catch invertebrate species, the snail Olivancillaria urceus and the sea star Luidia senegalensis. Sediment from the collection area was also investigated. Utilizing multiple isolation approaches, 134 isolates were obtained from the invertebrates and sediment. Small-subunit rRNA (16S) gene sequencing revealed that the isolates belonged to Proteobacteria, Firmicutes and Actinobacteria phyla and were distributed among 28 genera. Several genera known for their capacity to produce bioactive natural products (Micromonospora, Streptomyces, Serinicoccus and Verrucosispora) were retrieved from the invertebrate samples. To query the bacterial isolates for their ability to produce bioactive metabolites, all strains were fermented and fermentation extracts profiled by UP LC-HRMS and tested for antimicrobial activity. Four strains exhibited antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus warneri.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00203-016-1290-9 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Morphological, physiological and transcriptional analyses provide insights into the biosynthesis of phenolics in Juniperus rigida under UV-B treatment.
Plant Physiol Biochem
January 2025
College of Forestry, Northwest A & F University, Yangling, 712100, China; Shaanxi Key Laboratory of Economic Plant Resources Development and Utilization, Northwest A & F University, Yangling, 712100, China. Electronic address:
Phenolics play a crucial role in plant defense mechanisms against increased UV-B radiation. Due to their significant medicinal properties, the phenolic compounds produced by Juniperus rigida have great potential as valuable sources for medicine. However, the process of synthesizing J.
View Article and Find Full Text PDFL. (Anacardiaceae) fruits flours at different maturation stages: Drying kinetics, mathematical modelling, characterization and correlation analysis.
Heliyon
January 2025
University of Campinas, School of Food Engineering, 13056-405, Campinas, SP, Brazil.
The aim of this study was to examine the drying kinetics of L. fruits at various maturation stages (I to V) using a range of mathematical models (Henderson and Pabis, Lewis, Logarithmic, Midilli, and Page). Additionally, an assessment of the resulting flours' quality was conducted.
View Article and Find Full Text PDFActivation of Primary C-H Bonds in Oxidative Cyclizations of Tambjamines Catalyzed by Rieske Oxygenases TamC and TamC.
J Am Chem Soc
January 2025
Department of Chemistry, Queen's University, Kingston, ON K7L 3N6, Canada.
Tambjamines are complex bipyrrole-containing natural products that possess promising bioactive properties. Although is known to produce both cyclic tambjamine MYP1 and the linear precursor (YP1), the biosynthetic machinery used to catalyze the site-selective oxidative carbocyclization at the unactivated 1° carbon of YP1 has remained unclear. Here, we demonstrate that a three-component Rieske system consisting of an oxygenase (TamC) and two redox partner proteins is responsible for this unprecedented activity on YP1 and potentially, a non-native substrate (BE-18591).
View Article and Find Full Text PDFDevelopment of electrospun whey protein isolate nanofiber mat for omega-3 nanoencapsulation: Microstructural and physical property analysis.
Int J Biol Macromol
January 2025
Department of Food Science and Technology, Sari Agricultural Science and Natural Resources University, PO BOX 578, Sari, Mazandaran, Iran.
This study aimed to develop bead-free nanofibers for effective omega-3 encapsulation using optimal mixing ratios of whey protein isolate (WPI)/polyvinyl alcohol (PVA) blends via electrospinning method. Various WPI-PVA ratios (100:0, 90:10, 80:20, 70:30, 60:40, 50:50 v/v) were examined for surface tension, viscosity, and conductivity. SEM images revealed uneven nanofibers with bead at 90:10 and 80:20 ratios, while the 70:30 ratio produced uniform and bead-free nanofibers with an average diameter of 262.
View Article and Find Full Text PDFSystematic molecular dissection of key intermediates in xanthones biosynthesis in Cudrania tricuspidata and establishment of a viable heterologous expression system.
Plant Physiol Biochem
January 2025
Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China. Electronic address:
The major phytochemicals in the roots of Cudrania tricuspidata are prenylated xanthones, exhibiting significant structural diversity and bioactive properties, such as anti-inflammatory, antioxidative, and antitumor effects. The biosynthetic pathways of these compounds have not yet been resolved, limiting their production through synthetic biology. In this study, benzoyl-coenzyme A (CoA) ligase (BZL), benzophenone synthase (BPS), and benzophenone 3'-hydroxylase (B3'H) transcripts involved in the biosynthesis of xanthone were cloned and characterized from C.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!