AI Article Synopsis
- The study investigates the effectiveness of fine-needle aspiration biopsy with thyroglobulin measurement (FNAB-Tg) for diagnosing cervical lymph node metastases in patients with papillary thyroid cancer prior to surgery.
- Ultrasonography-guided FNAB was performed on 92 patients, revealing that 67 out of 105 lymph nodes had metastasis post-surgery.
- FNAB-Tg demonstrated high sensitivity (100%) and overall accuracy (95.2%), making it a valuable diagnostic tool in this context.
Article Abstract
Objective: To study the role of fine-needle aspiration biopsy and thyroglobulin measurement (FNAB-Tg) in diagnosing cervical lymph node (CLN) metastases in patients with papillary thyroid cancer (PTC) before thyroidectomy.
Methods: Ultrasonography (US)-guided FNAB was performed on 92 patients with PTCs with 105 CLNs before surgery. The wash-out of the FNAB-Tg level was detected.
Results: Based on the final pathology, 67 lymph nodes (LNs) were positive for metastasis, and 38 LNs were negative for metastasis. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of FNAB-Tg in thyroidectomized patients was 100%, 86.8%, 95.2%, 97.3%, and 95.2%, respectively.
Conclusions: FNAB-Tg is a useful technique for diagnosing CLN metastasis of PTC before thyroidectomy.
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| http://dx.doi.org/10.5414/CP202642 | DOI Listing |
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