Objective: To inform primary care screening and preventive intervention efforts, the authors examined the screening efficiency of the parent version of the Strengths and Difficulties Questionnaire (SDQP4-16) for persistent disorders relative to transient disorders and its capacity to distinguish between the two.
Methods: Persistence and transience in preschool-onset psychiatric disorders were identified by using data from a large population-based cohort study in Norwegian children initially assessed at age 4 and followed up at age 6 (n = 1038). Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, diagnoses at both time points were assigned by using the Preschool Age Psychiatric Assessment Interview, against which the SDQP4-16 was compared through receiver operating characteristics analysis.
Results: The screening efficiency for persistent disorders exceeded that for transient disorders with a specificity of 86.1%, a sensitivity of 79.3%, and an area under the curve value of 0.85. The SDQP4-16 was able to discriminate persistent disorders from transient disorders at an area under the curve value of 0.71. At the selected cutoff of 10, the negative predictive value was 99.6%, whereas the positive predictive value was 9.5%, partly due to the low prevalence (1.8%) of persistent disorders.
Conclusions: The SDQP4-16 is a sensitive tool for detecting persistent psychiatric disorders in young children. However, a large proportion of positive screens are nonpersistent cases, as indicated by the high false-positive rate. Thus, the clinical utility of the SDQP4-16 in primary care screening for persistent disorders is uncertain, particularly in samples in which the rate of psychiatric disorders is low.
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http://dx.doi.org/10.1542/peds.2015-1648 | DOI Listing |
J Clin Psychol
January 2025
Department of Clinical Psychology and Psychobiology, The Institute of Neurosciences, Universitat de Barcelona, Barcelona, Spain.
Based on the repertory grid technique, we developed Explore Your Meanings (EYME), a digital platform that helps patients explore identity values and internal conflicts using virtual reality (VR). EYME was part of a research project treating depression in young adults, including 10 weekly, 1-h sessions aimed at changing personal constructs-cognitive schemas that shape how individuals interpret reality. We present the case of Mary, a 21-year-old woman diagnosed with persistent major depressive disorder and social phobia.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
January 2025
Department of Biochemistry, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, , 11829, Cairo, Egypt.
Globally, the incidence and death rates associated with cancer persist in rising, despite considerable advancements in cancer therapy. Although some malignancies are manageable by a mix of chemotherapy, surgery, radiation, and targeted therapy, most malignant tumors either exhibit poor responsiveness to early identification or endure post-treatment survival. The prognosis for prostate cancer (PCa) is unfavorable since it is a perilous and lethal malignancy.
View Article and Find Full Text PDFEur Child Adolesc Psychiatry
January 2025
School of Psychology, Centre for Innovation in Mental Health, University of Southampton, University Road, Southampton, SO17 1BJ, UK.
The directionality of the relationship between adolescent alcohol consumption and mental health difficulties remains poorly understood. This study investigates the longitudinal relationship between alcohol use frequency, internalizing and externalizing symptoms from the ages of 11 to 17. We conducted a random-intercept cross-lagged panel model across three timepoints (ages: 11yrs, 14yrs, 17yrs; 50.
View Article and Find Full Text PDFRheumatol Int
January 2025
Department of Internal Medicine, General Hospital Oberndorf, Teaching Hospital of the Paracelsus Medical University, Salzburg, Austria.
Rheumatoid arthritis (RA) is a chronic autoimmune disease marked by systemic inflammation. While RA primarily affects the joints, its systemic effects may lead to an increased cerebro- and cardiovascular risk. Atherosclerosis of the carotid arteries is a significant risk factor for cerebrovascular events and serves as a surrogate marker for cardiovascular risk.
View Article and Find Full Text PDFMov Disord
January 2025
Department of Clinical Neurosciences, Parkinson and Movement Disorders Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Background: Magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy of ventral intermediate (Vim) nucleus is useful to treat drug-resistant tremor-dominant Parkinson's disease (TdPD), but tremor relapse may occur. Predictors of relapse have been poorly investigated so far.
Objective: The aim of this study is to evaluate the role of clinico-demographic, procedural, and neuroradiological variables in determining clinical response, relapse, and adverse events (AEs) in TdPD after MRgFUS Vim-thalamotomy.
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