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Regarding Bocklage et al. "Regarding Dettloff et al. Mammary Analog Secretory Carcinoma (MASC) Involving the Thyroid Gland: A Report of First 3 Cases".
Head Neck Pathol
June 2017
Head and Neck Pathology and Cytopathology, Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.
Mammary Analog Secretory Carcinoma (MASC) Involving the Thyroid Gland: A Report of the First 3 Cases.
Head Neck Pathol
June 2017
Department of Anatomic Pathology, Head and Neck Pathology and Cytopathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.
Salivary gland-type tumors have been rarely described in the thyroid gland. Mammary Analog Secretory Carcinoma (MASC) is a recently defined type of salivary gland carcinoma characterized by a t(12;15)(p13;q25) resulting in an ETV6-NTRK3 fusion gene. We report 3 cases of MASC involving the thyroid gland without clinical evidence of a salivary gland or breast primary; the clinico-pathologic characteristics are reviewed.
View Article and Find Full Text PDFUse of proteomic analysis to monitor responses to biological therapies.
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Proteomics has the potential to revolutionise diagnosis and disease management. Serum protein pattern profiling by surface-enhanced laser desorption/ionisation time of flight (SELDI-TOF) mass spectrometry is emerging as a novel approach to discover protein patterns capable of distinguishing disease and disease-free states with high sensitivity and specificity. This method has shown great promise for early diagnosis of ovarian cancer and is being applied to a range of pathological states.
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