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Iodine-123 Metaiodobenzylguanidine (I-123 MIBG) in Clinical Applications: A Comprehensive Review.
Pharmaceuticals (Basel)
November 2024
Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei 100233, Taiwan.
Iodine-123 metaiodobenzylguanidine (I-123 MIBG) is a crucial radiopharmaceutical widely used in nuclear medicine for its diagnostic capabilities in both cardiology and oncology. This review aims to present a comprehensive evaluation of the clinical applications of I-123 MIBG, focusing on its use in diagnosing and managing various diseases. In cardiology, I-123 MIBG has proven invaluable in assessing cardiac sympathetic innervation, particularly in patients with heart failure, where it provides prognostic information that guides treatment strategies.
View Article and Find Full Text PDFDiagnostic Value of Nuclear Hybrid Imaging in Malignant Struma Ovarii: A Systematic Review of Case Reports.
Diagnostics (Basel)
November 2024
Faculty of Medicine, Department of Medical Imaging and Nuclear Medicine, "Iuliu Hațieganu" University of Medicine and Pharmacy, 8 V. Babeș St., 400006 Cluj-Napoca, Romania.
Background: Struma ovarii is a rare tumor, a type of ovarian mature teratoma consisting over 50% of its mass in thyroid ectopic tissue; 5% to 10% of cases, as described in the literature, are malignant and well known as malignant struma ovarii or thyroid cancer from struma ovarii. Due to the limited number of malignant struma ovarii cases, the diagnostic and therapeutic approach of malignant struma ovarii lacks in standardization.
Methods: We performed a comprehensive search on the English language PubMed and Google Scholar.
Convention vs. Innovation II: Skin biopsy for synuclein inclusions will replace dopamine transporter imaging for Parkinson disease diagnosis.
Parkinsonism Relat Disord
September 2024
Parkinson Disease and Movement Disorders Program, Cleveland Clinic Lou Ruvo Center for Brain Health, 888 W. Bonneville Avenue, 89106, Las Vegas, NV, United States. Electronic address:
Evaluation of Improved Imaging Properties with Tungsten-Based Parallel-Hole Collimators: A Monte Carlo Study.
World J Nucl Med
June 2024
Department of Medical Radiation Physics, Lund, Lund University, Lund, Sweden.
Article Synopsis
- A parallel-hole collimator is used in a special camera system to only let through certain tiny particles (photons) from radioactive sources, helping to figure out where they come from.
- The study looked at using tungsten alloys instead of the usual lead material for the collimator to see if they were better.
- Tests showed that tungsten and its alloys gave clearer images and better details than the lead collimators for different radioactive sources.
Theranostics of Thyroid Cancer.
Semin Nucl Med
July 2024
Department of Oncology and Nuclear Medicine, University Hospital Center Sestre Milosrdnice, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia.
Molecular imaging is pivotal in evaluating and managing patients with different thyroid cancer histotypes. The existing, pathology-based, risk stratification systems can be usefully refined, by incorporating tumor-specific molecular and molecular imaging biomarkers with theranostic value, allowing patient-specific treatment decisions. Molecular imaging with different radioactive iodine isotopes (ie, I, I, I) is a central component of differentiated carcinoma (DTC)'s risk stratification while [F]F-fluorodeoxyglucose ([F]FDG) PET/CT is interrogated about disease aggressiveness and presence of distant metastases.
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