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Prevalence and Prognostic Impact of Diabetes in Takotsubo Syndrome: Insights from the Tokyo Cardiovascular Care Unit Network Registry.
Am J Cardiol
November 2024
Tokyo CCU Network Scientific Committee, Tokyo, Japan.
Article Synopsis
- Diabetes is a significant risk factor for cardiovascular diseases but exhibits a "diabetes paradox" in Takotsubo syndrome, where it may not negatively affect outcomes, although this remains debated.
- In a study analyzing 1,226 Takotsubo syndrome patients, the prevalence of diabetes was found to be similar to that of the general population (17.0% vs. 15.8%).
- The study concluded that diabetes does not have a protective effect in Takotsubo syndrome and may even be linked to higher in-hospital mortality rates, challenging the belief that diabetes could be beneficial in this context.
Diabetes associates with mortality in critically ill patients with SARS-CoV-2 pneumonia: No diabetes paradox in COVID-19.
Heliyon
August 2023
Graduate Program in Medical Sciences: Endocrinology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
Background: Diabetes mellitus (DM) is not associated with increased mortality in critically ill patients, a phenomenon known as the "diabetes paradox". However, DM is a risk factor for increased mortality in patients with COVID-19. This study aims to investigate the association of DM and stress-induced hyperglycemia at intensive care unit (ICU) with mortality in this population.
View Article and Find Full Text PDFTakotsubo syndrome: Does "Diabetes Paradox" exist?
Heart Lung
April 2021
Icahn School of Medicine at Mount Sinai, New York, New York, USA; Division of Cardiology, Elmhurst Hospital Center, Elmhurst, New York, USA. Electronic address:
Background: Previous small-scale studies have reported conflicting findings regarding the prevalence of diabetes mellitus (DM) and its association with outcomes in patients with takotsubo syndrome (TTS) OBJECTIVE: We sought to assess the prevalence of DM and its association with outcomes in TTS patients.
Methods: Nationwide inpatient sample (NIS) was queried to extract patient information from January 1, 2009 to September 30, 2015. Propensity score matching (PSM) was done to compare mortality and other in-hospital outcomes.
Predictors of oedema in Tako-Tsubo cardiomyopathy: new insights into the diabetes paradox.
J Cardiovasc Med (Hagerstown)
June 2019
Servicio de Cardiología.
A population-based study of the diabetes paradox in stress cardiomyopathy.
N Z Med J
November 2018
Department of Cardiology, Christchurch Hospital, Christchurch.
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