Sporothrix globosa is a thermo-dimorphic fungus belonging to a pathogenic clade that also includes Sporothrix schenckii, which causes human and animal sporotrichosis. Here, we present the first genome assemblies of two S. globosa strains providing data for future comparative genomic studies in pathogenic Sporothrix species.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203775 | PMC |
http://dx.doi.org/10.1093/gbe/evw230 | DOI Listing |
EBioMedicine
December 2024
Department of Laboratory Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, PR China; Zhejiang Key Laboratory of Clinical in Vitro Diagnostic Techniques, Hangzhou, 310003, PR China; Institute of Laboratory Medicine, Zhejiang University, Hangzhou, 310003, PR China. Electronic address:
Background: While metagenomic next-generation sequencing (mNGS) has been acknowledged as a valuable diagnostic tool for infections, its clinical validity and impact on patient management when using fresh tissue samples remains uncertain.
Methods: We conducted a retrospective cross-sectional study involving patients who underwent tissue mNGS at a tertiary hospital in China from February 2021 to February 2024, aiming to assess its ability to detect plausible pathogens and its clinical validity and impact.
Findings: A total of 520 mNGS results from 508 patients were analysed, detecting plausible pathogens in 302 (58.
J Invest Dermatol
November 2024
Department of Dermatology and Venerology, First Hospital of Jilin University, Changchun, China. Electronic address:
Front Med (Lausanne)
September 2024
Department of Dermatology, The Second Hospital of Jilin University, Changchun, China.
Med Mycol Case Rep
December 2024
Department of Dermatology, International University of Health and Welfare Narita Hospital, 852 Hatakeda, Narita, Chiba, 286-8520, Japan.
Clin Cosmet Investig Dermatol
September 2024
Department of Dermatology, Beijing Tongren Hospital, Capital Medical University, Beijing, People's Republic of China.
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