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A Retrospective Pragmatic Two-Center Clinical Study to Evaluate the Clinical Outcome of Triple-Frequency Ultrasound in the Treatment of Mild-to-Severe Acne Vulgaris.
J Cosmet Dermatol
November 2024
Wellcomet GmbH, Bruchsal, Germany.
Objectives: Earlier, quickly alternating dual-frequency ultrasound waves (LDM technology) were successfully applied for the treatment of different inflammatory skin conditions such as rosacea and acne. In this retrospective pragmatic two-center clinical study, we applied the triple-frequency LDM (TF-LDM) technology with frequencies of 1/3/10 and 3/10/19 MHz for the treatment of mild-to-severe acne skin to assess the effectivity and sustainability of the treatment outcomes.
Methods: Twenty-two patients with mild-to-severe acne were included in this study: 11 patients were treated with TF-LDM (1/3/10 MHz), and other 11 patients-with TF-LDM (3/10/19 MHz).
The treatment efficacy of 7.5% dapsone gel in papulopustular rosacea: a prospective study.
Cutan Ocul Toxicol
December 2024
Dermatology and Venereology Department, Başakşehir Çam and Sakura City Hospital, İstanbul, Turkey.
Introduction: Topical dapsone has a level A recommendation for the treatment of papulopustular rosacea; however, its treatment efficacy has not been studied previously. The aim of this study is to evaluate the safety and efficacy of topical 7.5% dapsone gel applied once daily at night in the treatment of papulopustular rosacea.
View Article and Find Full Text PDFProtease-Activated Receptor 2 in inflammatory skin disease: current evidence and future perspectives.
Front Immunol
September 2024
Department of Dermatology, Huashan Hosptial, Fudan University, Shanghai, China.
Article Synopsis
- PAR2 is a special protein found in the skin that gets activated by certain enzymes and plays a big role in skin inflammation and healing.
- It helps control things like itching and pain, and is linked to skin problems like acne, rosacea, psoriasis, and eczema.
- Researchers are looking into new treatments that target PAR2 to help improve these skin conditions.
Meta-Analysis of the Efficacy of Intense Pulsed Light and Pulsed-Dye Laser Therapy in the Management of Rosacea.
J Cosmet Dermatol
December 2024
Department of Dermatology, Shenzhen Center for Chronic Disease Control, Shenzhen, Guangdong, China.
Objective: The primary aim of this systematic review and meta-analysis was to synthesize and compare the clinical efficacy of intense pulsed light (IPL) and pulsed-dye laser (PDL) therapies for the management of rosacea.
Methods: The literatures were searched in the Web of Science, PubMed, Embase, and Cochrane Library databases to identify relevant studies investigating the use of IPL and PDL for the treatment of rosacea. Screening of the retrieved articles and data extraction were performed as per the pre-established inclusion and exclusion criteria.
Detection of demodex mites in papulopustular rosacea using microscopic examination and polymerase chain reaction: a comparative case-control study.
Arch Dermatol Res
July 2024
Section of Dermatology, Department of Health Sciences, University of Genoa, IRCCS - Ospedale Policlinico San Martino, Genoa, Italy.
Article Synopsis
- - The study investigates the role of Demodex mites in rosacea, comparing the effectiveness of PCR testing to traditional microscopic examination for identifying infestations.
- - Results showed that patients with rosacea had significantly higher rates of Demodex detection compared to controls, with PCR being much more sensitive than microscopy for detection.
- - The findings suggest a correlation between the presence of Demodex mites and the severity of facial symptoms, indicating that the scalp may also harbor these mites; additional research on non-invasive sampling methods like PCR is recommended.
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