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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.116.004262DOI Listing

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Article Synopsis
  • Recent studies have shown that colchicine may lower the risk of major cardiovascular events in patients with coronary artery disease, but its effects on peripheral artery disease (PAD) is unclear.
  • The researchers conducted two "emulated" trials comparing colchicine to non-steroidal anti-inflammatory drugs (NSAIDs) in patients with gout and PAD, using data from Medicare patients over a 12-year period.
  • The results indicated no significant difference in the risk of major adverse events between the colchicine and NSAID groups, suggesting that colchicine might not have a marked impact on lowering these risks in PAD patients.
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