Purpose: To evaluate the sequelae due to epidemic viral conjunctivitis (VC) for a possible association with inflammatory trachoma in schoolchildren.

Methods: A cross-sectional survey was performed of 2,093 schoolchildren in public schools in Sao Paulo State, Brazil. The exams were conducted according to the WHO definitions to detect trachoma. We evaluated the prevalence and the association between inflammatory trachoma and sequelae due to VC.

Results: The prevalence of inflammatory trachoma in schoolchildren in Botucatu City was 2.9% (CI: 1.2-17.3%). The prevalence of sequelae from VC was 0.007% (CI: 0 to 0.033%). Acute bacterial conjunctivitis was detected in 0.001%. There was no association between inflammatory trachoma and VC-related sequelae or acute bacterial conjunctivitis.

Conclusion: An outbreak of epidemic VC can lead to definitive sequelae in the tarsal conjunctiva. The sequelae from VC were detected in 0.007% of the schoolchildren and were not associated with inflammatory trachoma.

Download full-text PDF

Source
http://dx.doi.org/10.1080/08820538.2016.1208762DOI Listing

Publication Analysis

Top Keywords

inflammatory trachoma
24
association inflammatory
12
sequelae epidemic
8
epidemic viral
8
viral conjunctivitis
8
associated inflammatory
8
acute bacterial
8
sequelae
7
trachoma
7
inflammatory
6

Similar Publications

Introduction: Trachoma is caused by the bacterium (). The WHO recommends the SAFE strategy for trachoma elimination: Surgery for trichiasis, Antibiotics, Facial cleanliness and Environmental improvement. Multiple rounds of SAFE implementation have proven insufficient to eliminate trachoma in Ethiopia, where over 50% of the global trachoma burden remains.

View Article and Find Full Text PDF
Article Synopsis
  • Trachoma is still a significant health issue in parts of Cameroon, particularly in the northern regions, where surveys from 2016-2022 revealed ongoing cases of active trachoma and trichiasis, despite previous interventions.
  • A total of 151,800 individuals were examined in these surveys, and findings indicated that two evaluation units exceeded the 5% threshold for active trachoma, while ten units exceeded the 0.2% threshold for trichiasis.
  • Continued intervention efforts, including mass antibiotic distribution and improved surgical access, are needed to address these health challenges, with future assessments required to gauge progress towards eliminating trachoma as a public health concern.
View Article and Find Full Text PDF
Article Synopsis
  • Trachoma is the leading infectious cause of blindness globally, primarily caused by serovars A-C of the bacterium Chlamydia trachomatis (Ct).
  • The disease spreads through direct or indirect contact with infected ocular and nasal secretions, often in areas with poor hygiene and crowded living conditions.
  • Chronic inflammation from repeated infections in early childhood can lead to severe complications like conjunctival scarring, trichiasis, corneal opacity, and ultimately, visual impairment.
View Article and Find Full Text PDF

Association of polymorphisms of and genes with trachoma disease.

J Genet

July 2024

Faculty of Chemical Sciences and Faculty of Medicine, University of Colima, Av. Universidad #333, Col. Las Viboras, C.P. 28040 Colima, Colima,

Article Synopsis
  • - Trachoma is the leading cause of infectious blindness worldwide, particularly affecting indigenous Mayan populations in Chiapas, Mexico, and is linked to genetic factors that may increase the risk of developing severe cases.
  • - A study involving 51 individuals with late-stage trachoma and 102 controls identified specific genetic polymorphisms (SNPs) related to inflammation, particularly in genes like BIRC3 and ABCG2, that correlate with heightened risk of the disease.
  • - Key findings indicate that certain alleles, specifically the T allele of rs11807619, the C allele of rs932335, and the D allele of rs4340 in the ACE gene, are significantly associated with increased risk of late-stage tr
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!